miRNA and isomiR profiles in MIN6 cells, primary human beta cells and human islet.

<p>(<b>A</b>) A heatmap is shown depicting the Pearson correlation coefficients of miRNA profiles between pairs of samples analyzed in this study. (<b>B</b>) The x-axis depicts highly expressed miRNAs ordered from left to right by decreasing maximal expression across all samples. The y-axis depicts the Log10 of the average read count per million. Each dot represents a miRNA. miRNAs from a homogenous locus (a pre-miRNA that produces only one mature miRNA per arm of the hairpin) are in gray. miRNAs from a heterogeneous locus (a pre-miRNA that produces more than one mature miRNA per arm of the hairpin) are either pink (5′-reference) or blue (5′-shifted).