<p>The number of G<sub>183</sub>-specific (grey bars) and M2<sub>82</sub>-specific (black bars) IL-4 (A) or IFNγ (B) producing splenocytes was determined by ELISPOT in cells harvested 5 days post-challenge. The data are presented as cytokine spots/10<sup>6</sup> splenocytes. Error bars represent the SEM from n=5 mice per group. *, #, p<0.05, significant difference as determined by one-way ANOVA and Dunnett’s test, compared with PBS vaccinated control mice (*) or compared to live RSV A2 vaccinated mice (#).</p
<p>(a) IFN-γ, (b) IL-2, and (c) IL-4 mRNA levels in splenocytes from mice were determined at week 4 ...
<p>BALB/c mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). Where indicated, mice were in...
<p>IFN-γ protein amount was determined in the (A) lung and (B) serum at 0, 2, and 4 days following R...
<p>Mice were vaccinated twice with RSV virosomes, RSV-MPLA virosomes and control vaccines as in <a h...
<p>BALB/c mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). CD3<sup>+</sup> gated, CD4<su...
<p>IFN-γ (Panel A) and IL-5 (Panel B) production in splenocyte cultures after stimulation with inact...
<p>After RSV B (KR/B/10-12) challenge, all mice (n = 4/group) were sacrificed and lung mononuclear c...
<p>BALB/c mice and IL-10<sup>−/−</sup> mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). ...
<p>Mice were vaccinated with 50 µg of RSV G nanoparticles, 10 µg of purified G protein emulsified 1:...
<p>Mice were i.m. vaccinated with formalin inactivated RSV A2, rested for at four weeks and i.n chal...
<p>Ifitm3<sup>-/-</sup> or wild type littermate control mice were infected i.n. with 5x10<sup>5</sup...
<p>IFN-γ and IL-4 production by splenocytes of mice were measured at week 4 after vaccination with r...
<p>Mice were vaccinated twice with RSV virosomes, RSV-MPLA virosomes or controls (HNE, live virus an...
<p>(A) FI-mock- and FI-RSV-vaccinated mice were monitored daily for airway obstruction using a whole...
<p>BALB/c mice were immunized IN with RSV-virosomal vaccine formulations (5 µg of protein) or HNE. C...
<p>(a) IFN-γ, (b) IL-2, and (c) IL-4 mRNA levels in splenocytes from mice were determined at week 4 ...
<p>BALB/c mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). Where indicated, mice were in...
<p>IFN-γ protein amount was determined in the (A) lung and (B) serum at 0, 2, and 4 days following R...
<p>Mice were vaccinated twice with RSV virosomes, RSV-MPLA virosomes and control vaccines as in <a h...
<p>BALB/c mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). CD3<sup>+</sup> gated, CD4<su...
<p>IFN-γ (Panel A) and IL-5 (Panel B) production in splenocyte cultures after stimulation with inact...
<p>After RSV B (KR/B/10-12) challenge, all mice (n = 4/group) were sacrificed and lung mononuclear c...
<p>BALB/c mice and IL-10<sup>−/−</sup> mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). ...
<p>Mice were vaccinated with 50 µg of RSV G nanoparticles, 10 µg of purified G protein emulsified 1:...
<p>Mice were i.m. vaccinated with formalin inactivated RSV A2, rested for at four weeks and i.n chal...
<p>Ifitm3<sup>-/-</sup> or wild type littermate control mice were infected i.n. with 5x10<sup>5</sup...
<p>IFN-γ and IL-4 production by splenocytes of mice were measured at week 4 after vaccination with r...
<p>Mice were vaccinated twice with RSV virosomes, RSV-MPLA virosomes or controls (HNE, live virus an...
<p>(A) FI-mock- and FI-RSV-vaccinated mice were monitored daily for airway obstruction using a whole...
<p>BALB/c mice were immunized IN with RSV-virosomal vaccine formulations (5 µg of protein) or HNE. C...
<p>(a) IFN-γ, (b) IL-2, and (c) IL-4 mRNA levels in splenocytes from mice were determined at week 4 ...
<p>BALB/c mice were infected with 10<sup>6</sup> PFU RSV i.n. (day 0). Where indicated, mice were in...
<p>IFN-γ protein amount was determined in the (A) lung and (B) serum at 0, 2, and 4 days following R...