Effects of Src siRNA and 1% oxygen on motility of U251 cells.

<p>(a) plots the matrigel invasion assay of U251 cells in 1% and 21% ambient oxygen in the presence of Dasatinib (100 nM) or vehicle (DMSO). * indicates a two-sample two-tailed ttest <i>p</i><0.05 as compared to 1% DMSO. (b) displays western blots showing downregulation of c-src by siRNA. (c) plots the matrigel invasion data of U251 cells transfected by negative control (blue) and c-src siRNA (red) in 5% and 21% ambient oxygen. (d) plots the matrigel invasion data of U251 cells transfected by negative control (blue) and c-src siRNA (red) in 1% and 21% ambient oxygen. * indicates a two-sample two-tailed ttest <i>p</i><0.05 as compared to 1% or 5% negative control siRNA.