NWASP siRNA inhibits low oxygen-induced hypermotility.

<p>(a)-(c) plot, respectively, the matrigel motility data of D54, U87, and LN229, transfected by negative control (blue) and NWASP siRNAs (red) cultured in 5% and 21% ambient oxygen. (d) plots the matrigel motility data of LN229, transfected by negative control siRNA (blue) and the second NWASP siRNA (red) cultured in 1% and 21% ambient oxygen. (e)-(h) are western blots showing downregulation of NWASP/p-NWASP by siRNA in (a)-(d), respectively. * indicates a two-sample two-tailed ttest <i>P</i><0.05 as compared to 5% or 1% negative control siRNA.