Changes in ROS generation, p47phox and ECM expressions after knockdown XBP1S by siRNA.

<p>A, B and C: Western blot analysis on XBP1S and p47phox levels in the cultured MCs before and after XBP1S siRNA transfection for 48 h (mean ± SEM, n = 6). D: Observation of ROS generation by DHE fluorescent probe assay in the cultured MCs before and after XBP1S siRNA transfection for 48 h (mean ± SEM, n = 7). E: collagen IV and fibronectin levels were determined by western blot analysis before and after XBP1S siRNA transfection for 48 h (mean ± SEM, n = 5) *<i>p</i><0.05 compared to negative control; **<i>p</i><0.01 compared to negative control.