Engulfment mutations enhance ER stress resistance.

<p>(A) Mutations in <i>ced-1(e1735), ced-6(n1813)</i> and <i>ced-7(n1892)</i> with or without <i>pgrn-1(tm985)</i> in the background were tested for ER stress resistance by tunicamycin (TM) treatment. (B) Mutations in <i>ced-2(e1752), ced-5(n1812)</i> and <i>ced-10(n3246)</i> with or without <i>pgrn-1(tm985)</i> in the background were tested for ER stress resistance by tunicamycin treatment. (C) Mutations in <i>abl-1(ok171), abi-1(ok640)</i> and <i>abi-1(tm494)</i> were tested for ER stress resistance by tunicamycin treatment. Results shown are representative of at least 2 experiments except in the case of (C) which was performed once. Error bars represent standard deviation. Statistical comparisons are to N2 control (ANOVA with Bonferroni post-tests). n.s. not significant, *p<0.05, **p<0.01, ***p<0.001. For additional statistical data, see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003714#pgen.1003714.s015" target="_blank">Table S3A</a>, B, and D.