<p>The weight of a typical symmetrically dividing mutant stem cell lineage, , relative to the weight of an asymmetrically dividing mutant stem cell lineage, , is plotted as a function of the number of stem cell divisions, . Here, , , and 20 batches of simulations were performed to calculate the mean and the standard deviation.</p
<p>Measurements are based on the phenotype of progenitors and progeny before cell septation. 1–6 are...
The growth rate discrepancy, ρ, exerts a dominant effect upon whether the final population sizes fav...
Stem cell divisions are either asymmetric-in which one daughter cell remains a stem cell and one doe...
Traditionally, it has been held that a central characteristic of stem cells is their ability to divi...
Traditionally, it has been held that a central characteristic of stem cells is their ability to divi...
<p>Plotted is the quantity in formula (4) as a function of the mutation rate, . The percentage of th...
<p>(A) A fraction <i>s</i> of stem cells divide symmetrically while the others divide asymmetrically...
<p>The case of symmetrically dividing stem cells, same as in <a href="http://www.plosone.org/article...
Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant...
<p>The fastest pathway of both cases is DGR, but the probabilities of stem-cell division are markedl...
<p>(A) Homeostasis of stem cell number may be achieved by invariant asymmetric renewals. (B) Alterna...
<p>The quantity , which corresponds to , is plotted as a function of the mutation rate, , for three ...
<p>The results of numerical simulations are presented as points connected with dotted lines (standar...
Stem cells are defined by both their ability to make more stem cells, a property known as 'self...
<p>An example of tissue formation without inhibition to symmetric division is shown in a), and its c...
<p>Measurements are based on the phenotype of progenitors and progeny before cell septation. 1–6 are...
The growth rate discrepancy, ρ, exerts a dominant effect upon whether the final population sizes fav...
Stem cell divisions are either asymmetric-in which one daughter cell remains a stem cell and one doe...
Traditionally, it has been held that a central characteristic of stem cells is their ability to divi...
Traditionally, it has been held that a central characteristic of stem cells is their ability to divi...
<p>Plotted is the quantity in formula (4) as a function of the mutation rate, . The percentage of th...
<p>(A) A fraction <i>s</i> of stem cells divide symmetrically while the others divide asymmetrically...
<p>The case of symmetrically dividing stem cells, same as in <a href="http://www.plosone.org/article...
Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant...
<p>The fastest pathway of both cases is DGR, but the probabilities of stem-cell division are markedl...
<p>(A) Homeostasis of stem cell number may be achieved by invariant asymmetric renewals. (B) Alterna...
<p>The quantity , which corresponds to , is plotted as a function of the mutation rate, , for three ...
<p>The results of numerical simulations are presented as points connected with dotted lines (standar...
Stem cells are defined by both their ability to make more stem cells, a property known as 'self...
<p>An example of tissue formation without inhibition to symmetric division is shown in a), and its c...
<p>Measurements are based on the phenotype of progenitors and progeny before cell septation. 1–6 are...
The growth rate discrepancy, ρ, exerts a dominant effect upon whether the final population sizes fav...
Stem cell divisions are either asymmetric-in which one daughter cell remains a stem cell and one doe...
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