Phosphorylation of synapsins I and II in female mice.

<p>Western blot of mouse brain extracts used a mixture of antibodies to synapsin I (Syn1) and β-actin (A), a mixture of antibodies to synapsins phosphorylated at Ser-9 and β-actin (B), and a mixture of antibodies to synapsins phosphorylated at Ser-603 and β-actin (C). Panel D shows quantitative measurements of band intensities after normalization to β-actin. Data are expressed as means ± SEM (n=5 for each genotype). A two-tailed t-test with pairwise matching of adjacent lanes (WT vs. KO) was employed. *P < 0.05, **P < 0.01, ***P < 0.001 for KO vs. WT.