Effects of gain and loss of Mpc function on the oxygen consumption rate.

<p>The rate of oxygen consumption was measured in intact yeast cells corresponding to the indicated overexpression (A) or deletion strains (B). The control strain in the upper panel is wild type BY4741 with the empty overexpression vector and untransformed wild type in the lower panel. Data represent mean values +/− SD from at least three independent measurements. Mpc1 and Mpc2 overexpressing strains have significantly reduced oxygen consumption rates (p = 0.02), while Mpc3 overexpressing cells significantly increase the oxygen consumption rate (p = 0.05) according to the Students t-test (A). Oxygen consumption is significantly reduced (p = 0.05) in the <i>mpc1</i> and <i>mpc3</i> mutants as compared to wt according to the Students t-test (B).