<p>(<i>A</i>) BH<sub>4</sub> levels, (<i>B</i>) BH<sub>2</sub> levels, and (<i>C</i>) BH<sub>4</sub>/BH<sub>2</sub> ratio in lung from mice exposed to normoxia (NX) or 10, 21 and 40 days of hypoxia (HX 10d, HX 21d and HX 40d, respectively). Results are expressed as mean ± SEM from 6 experiments. * p<0.05, ** p<0.01, compared to NX.</p
Background. Severe obstructive sleep apnea (OSA) with chronic intermittent hypoxia (IH) is common in...
<p>Values are expressed as mean ± SEM. (A) Hypoxia significantly increased lung volumes in CREB<sup>...
<div><p>(A) Effects of breathing hypoxic (10%) oxygen on arterial blood oxygen tension (left graph) ...
<p>Graphs showing quantified data normalized to β-actin and representative Western-blotting for (<i>...
<p>WT and HEX-Tg (Tg) mice were placed in normoxic or hypoxic conditions for 10 weeks. (A) Pulmonary...
<p>(<i>A</i>) Graphs showing quantified data for eNOS dimer / monomer ratio and representative Weste...
<p><b>A,</b> Hematoxylin and eosin staining on representative lung specimens from <i>bcr−/−, abr−/−<...
<div><p>(A) Enhanced lung vascular permeability (left graph) and impairment of lung gas exchange (ri...
<div><p>(A) Exposure of IT LPS-injected mice to hypoxic (10%) oxygen levels for 48 h atmosphere lead...
<p>(<b>A</b>, <b>B</b>, <b>C</b>, <b>D</b>) Lung histology (H&E staining, 200x magnification) of mic...
International audienceBackground. Severe obstructive sleep apnea (OSA) with chronic intermittent hyp...
<p>RVSP from <i>bcr−/−, abr−/−</i> and <i>wt</i> mice with exposure to normoxia or hypoxia. <b>B,</b...
<p>ΔPAP was referenced to the onset of 180 min of hypoxic ventilation period (time set at 0). Normox...
<p>Representative photomicrographs of lung histology (H&E stain) of NB MIF KO, MIF TG and WT control...
<p>A–D: Paraffin-embedded lung sections from mice exposed to normoxia (7d, 20.8% O<sub>2</sub>) (A),...
Background. Severe obstructive sleep apnea (OSA) with chronic intermittent hypoxia (IH) is common in...
<p>Values are expressed as mean ± SEM. (A) Hypoxia significantly increased lung volumes in CREB<sup>...
<div><p>(A) Effects of breathing hypoxic (10%) oxygen on arterial blood oxygen tension (left graph) ...
<p>Graphs showing quantified data normalized to β-actin and representative Western-blotting for (<i>...
<p>WT and HEX-Tg (Tg) mice were placed in normoxic or hypoxic conditions for 10 weeks. (A) Pulmonary...
<p>(<i>A</i>) Graphs showing quantified data for eNOS dimer / monomer ratio and representative Weste...
<p><b>A,</b> Hematoxylin and eosin staining on representative lung specimens from <i>bcr−/−, abr−/−<...
<div><p>(A) Enhanced lung vascular permeability (left graph) and impairment of lung gas exchange (ri...
<div><p>(A) Exposure of IT LPS-injected mice to hypoxic (10%) oxygen levels for 48 h atmosphere lead...
<p>(<b>A</b>, <b>B</b>, <b>C</b>, <b>D</b>) Lung histology (H&E staining, 200x magnification) of mic...
International audienceBackground. Severe obstructive sleep apnea (OSA) with chronic intermittent hyp...
<p>RVSP from <i>bcr−/−, abr−/−</i> and <i>wt</i> mice with exposure to normoxia or hypoxia. <b>B,</b...
<p>ΔPAP was referenced to the onset of 180 min of hypoxic ventilation period (time set at 0). Normox...
<p>Representative photomicrographs of lung histology (H&E stain) of NB MIF KO, MIF TG and WT control...
<p>A–D: Paraffin-embedded lung sections from mice exposed to normoxia (7d, 20.8% O<sub>2</sub>) (A),...
Background. Severe obstructive sleep apnea (OSA) with chronic intermittent hypoxia (IH) is common in...
<p>Values are expressed as mean ± SEM. (A) Hypoxia significantly increased lung volumes in CREB<sup>...
<div><p>(A) Effects of breathing hypoxic (10%) oxygen on arterial blood oxygen tension (left graph) ...