<p>(A) The total cross-sectional area of the enteroids per well was measured to quantify the growth of the stem cells with and without ISEMFs (n = 2). (B) Time lapse images of the growth up to day 14. (C–F) Immunohistochemical staining of single ISC-derived enteroids and ISEMFs implanted <i>in vivo</i>. (C) H&E, (D) α-SMA, (E) Cdx2, and (F) PAS. The scale bar represents 100 µm in B and 50 µm in C through F. Asterisk indicates p<0.05 when compared to <i>No ISEMF</i>.</p
<p><b>A-F</b>, top panels: small intestine, bottom panels: large intestine (<b>A</b>) Hematoxylin an...
Organoids are three-dimensional in-vitro-grown cell clusters with near-native microanatomy that aris...
Porcine models are useful for investigating therapeutic approaches to short bowel syndrome and poten...
<p>Crypts were grown in culture media containing Rspo1, with or without ISEMF CM, and assessed after...
<p>Enteroid forming efficiency was measured in mono- and co-cultures with ISEMFs, with and without e...
<p>Crypts with and without ISEMFs were grown in culture media that contained Rspo1 and assessed afte...
<p>Crypts with and without ISEMFs were grown in culture media that contained Rspo1 and assessed afte...
<p>Crypts from the jejunum were plated in Matrigel for two days. Pam3CSK4 (400ng/mL), Poly I:C (40μg...
<p>Human crypts cultured on murine myofibroblasts in the presence of Wnt3a and FGF10 were processed ...
<p>Human small intestinal crypts cultured on murine myofibroblasts in the presence of Wnt3a and FGF1...
<p>Human small intestinal crypts on murine myofibroblasts were grown in culture for 11 days in the p...
The epithelium of the gastrointestinal tract is constantly renewed as it turns over. This process is...
Toxoplasma gondii and Cryptosporidium spp. can cause devastating pathological effects in humans and ...
Intestinal epithelial stem cells (IESC) have been an area of intense study for applications in tissu...
Intestinal stem cells (ISCs) require well-defined signals from their environment in order to carry o...
<p><b>A-F</b>, top panels: small intestine, bottom panels: large intestine (<b>A</b>) Hematoxylin an...
Organoids are three-dimensional in-vitro-grown cell clusters with near-native microanatomy that aris...
Porcine models are useful for investigating therapeutic approaches to short bowel syndrome and poten...
<p>Crypts were grown in culture media containing Rspo1, with or without ISEMF CM, and assessed after...
<p>Enteroid forming efficiency was measured in mono- and co-cultures with ISEMFs, with and without e...
<p>Crypts with and without ISEMFs were grown in culture media that contained Rspo1 and assessed afte...
<p>Crypts with and without ISEMFs were grown in culture media that contained Rspo1 and assessed afte...
<p>Crypts from the jejunum were plated in Matrigel for two days. Pam3CSK4 (400ng/mL), Poly I:C (40μg...
<p>Human crypts cultured on murine myofibroblasts in the presence of Wnt3a and FGF10 were processed ...
<p>Human small intestinal crypts cultured on murine myofibroblasts in the presence of Wnt3a and FGF1...
<p>Human small intestinal crypts on murine myofibroblasts were grown in culture for 11 days in the p...
The epithelium of the gastrointestinal tract is constantly renewed as it turns over. This process is...
Toxoplasma gondii and Cryptosporidium spp. can cause devastating pathological effects in humans and ...
Intestinal epithelial stem cells (IESC) have been an area of intense study for applications in tissu...
Intestinal stem cells (ISCs) require well-defined signals from their environment in order to carry o...
<p><b>A-F</b>, top panels: small intestine, bottom panels: large intestine (<b>A</b>) Hematoxylin an...
Organoids are three-dimensional in-vitro-grown cell clusters with near-native microanatomy that aris...
Porcine models are useful for investigating therapeutic approaches to short bowel syndrome and poten...