Secretions of End1/E6E7 cells modulate cytokine levels by DC: T cell-co-cultures in response to LPS.

<p>Monocyte derived dendritic cells (MDDCs) were incubated with fresh medium (No SM) or UT-SM, CpG-SM or Poly-SM for 24 hrs. Later MDDCs were stimulated with LPS (100 ng/ml) and autologous CD3<b>⁺</b> T cells for 24 hrs and spent media were analyzed for TNF-α (<b>A</b>) and IL-12 (<b>B</b>). Values represent mean ± SD of three experiments performed on different days. Level of significance (*p<0.05; ***p<0.001) was calculated by ANOVA test followed by Bonferroni analysis.