<p>Metastases are indicated by arrows. In the spine, metastases were observed using microcomputed tomography (Maximum Intensity Projection) and confirmed post-mortem by HES staining and immunohistology using anti-PSA (prostate specific antigen) and anti-PSGR antibodies (only one metastasis is presented). In the lungs, metastases were characterized by HES staining and immunohistology using anti-PSA and anti-PSGR antibodies.</p
The spine is one of the organs that is most affected by metastasis in cancer patients. Since the con...
<p>Metastasis frequency after in vivo metastasis selection cycles one to six of PC-3-GFP. After 6 cy...
<p><b>A–D.</b> H+E staining performed on 5 µm paraffin-embedded sections of lung from sample 5–8 BM ...
<p>(A) HE staining of brain and lung tissues. Arrows point to pathological mitotic figure. (B) X-ray...
<p>At 45 days after tumor cells injection, the animals injected with K5L and K5L-Luc cells were sacr...
<p>A) A large lung metastasis from a Krt8-CreERT2 Pten;Tgfbr2 mouse stained for Krt5 and Krt8 is sho...
<div><p>(A) Underside of skin from tumor-bearing mouse shows newly formed blood vessels surrounding ...
<p>2×10<sup>6</sup> PC-3 or PC-3-RFP cells were implanted into the right flank of nude mice. (a) Rea...
(A) Metastases to right lung (black arrows) is visualized at harvest in addition to primary tumor (w...
<p>Mouse no. 6 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0111881#pone...
<p>Shortly after mice were sacrificed, lungs were entirely resected and were fixed in formalin, hist...
<p>A) Number of pulmonary metastases in evaluable NOD/SCID mice four weeks after transplantation, ea...
<p>(<b>a</b>) The number of metastases observed in various tissues after mice sacrifice (white: untr...
Death related to prostate cancer is invariably due to the tumor metastasis (to lungs, skeleton and l...
<p>Eight days after leg resection, mice were sacrificed, and lung metastasis was evaluated. A: Gross...
The spine is one of the organs that is most affected by metastasis in cancer patients. Since the con...
<p>Metastasis frequency after in vivo metastasis selection cycles one to six of PC-3-GFP. After 6 cy...
<p><b>A–D.</b> H+E staining performed on 5 µm paraffin-embedded sections of lung from sample 5–8 BM ...
<p>(A) HE staining of brain and lung tissues. Arrows point to pathological mitotic figure. (B) X-ray...
<p>At 45 days after tumor cells injection, the animals injected with K5L and K5L-Luc cells were sacr...
<p>A) A large lung metastasis from a Krt8-CreERT2 Pten;Tgfbr2 mouse stained for Krt5 and Krt8 is sho...
<div><p>(A) Underside of skin from tumor-bearing mouse shows newly formed blood vessels surrounding ...
<p>2×10<sup>6</sup> PC-3 or PC-3-RFP cells were implanted into the right flank of nude mice. (a) Rea...
(A) Metastases to right lung (black arrows) is visualized at harvest in addition to primary tumor (w...
<p>Mouse no. 6 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0111881#pone...
<p>Shortly after mice were sacrificed, lungs were entirely resected and were fixed in formalin, hist...
<p>A) Number of pulmonary metastases in evaluable NOD/SCID mice four weeks after transplantation, ea...
<p>(<b>a</b>) The number of metastases observed in various tissues after mice sacrifice (white: untr...
Death related to prostate cancer is invariably due to the tumor metastasis (to lungs, skeleton and l...
<p>Eight days after leg resection, mice were sacrificed, and lung metastasis was evaluated. A: Gross...
The spine is one of the organs that is most affected by metastasis in cancer patients. Since the con...
<p>Metastasis frequency after in vivo metastasis selection cycles one to six of PC-3-GFP. After 6 cy...
<p><b>A–D.</b> H+E staining performed on 5 µm paraffin-embedded sections of lung from sample 5–8 BM ...