Metastases detection in immunodeficient mice inoculated with LNCaP cells.

<p>(<b>a</b>) The number of metastases observed in various tissues after mice sacrifice (white: untreated control mice, gray: mice treated with mineral oil, black: mice treated with 1 mM β-ionone in mineral oil). (<b>b</b>) Cumulative number of metastases, regardless of their location, as a function of the time elapsed between LNCaP cells inoculation and mice sacrifice (white: untreated control mice, gray: mice treated with mineral oil, black: mice treated with 1 mM β-ionone in mineral oil). Mice were sacrificed when tumor size exceeded 1,500 mm³. The number of sacrificed mice is indicated in brackets for each time point and each mice group. (<b>c</b>) Curves reporting the ratios of the number of metastases over the number of sacrificed mice as a function of the time (black dashed: untreated control mice, gray: mice treated with mineral oil, black: mice treated with 1 mM β-ionone in mineral oil).