The stroma of Foxd1DTA mutants is mispatterned.

<p>A–F: E13.5 control (A–C) and Foxd1DTA (D–F) kidney sections stained with renal stromal markers. E13.5 kidneys stained with Meis1/2 (A and D), Tenascin (B and E) and PDGFRB (C and F) show that mutant samples have disorganization with a lack of stromal tissue interdigitating between the nephron progenitor units. G–L: E16.5 control (G–I) and Foxd1DTA (J–L) kidney sections stained with renal stromal markers. The lack of organization is again apparent, with a thickened capsule (concave arrow) and lack of interdigitation (arrow). Low power PDGFRB images show a fused kidney and the lack of stromal organization (I and L). Scale bars A–H and J–K = 100 µm, I and L = 200 µm.