<p>U937 cells were treated with LPS or ASTA at the doses indicated. Groups include the following: Nuclear, Nrf2 protein levels in nuclear extracts; Cytosolic, Nrf2 protein levels in cytosolic fractions; panels on left show results of Western blot as appropriate. Plot on right shows the results of quantitative analysis. *<i>p</i><0.05 compared with control cells; <sup>§</sup><i>p</i><0.05 compared with LPS-treated cells.</p
(A) Knockdown of Nrf2 with siNrf2 in control and HT-treated (200 μM) normoxic and hypoxic cells. The...
<p>The cells were transfected with a scramble control siRNA or Nrf2 siRNA, and were then treated wit...
<p>A FACS: the average of the median signal intensities in cells stained with anti-NRF2 antibodies ...
<p>Western blots illustrate Nrf2 protein concentration in whole cell lysate and nuclear fraction usi...
<p>ARPE-19 cells were treated with the indicated concentrations of LM for 48 h, or 40 μmol/L of LA o...
<p>(A) Anti-NRF2 Western Blot of tissue cell lysates after siRNA to the indicated screening hits. Tr...
A) Western blot analysis for phosphorylated p38 and total p38 in WT (238RM) and AT (AT129RM) cells t...
<p>NF-kB (A) was analyzed as described in materials and methods; Nrf2 mRNA (A) was analyzed by quant...
<p>(A) AGS cells were treated with DAS, DADS, and DATS (20 µM of each). After 1 h, the cells were ha...
<p>Confluent mAECs were pre-incubated with 250 µg/mL of AST or ASIV for 2 h, then washed and incubat...
<p><b>A</b>. Schematic diagram showing characteristics of cell lines with low (upper panel), moderat...
<p>Cells were incubated with or without ASTA (10 µM) for 1 h, and then stimulated with LPS (10 µg/ml...
<p>(A) Representative Western blot analysis of the effect of DMF on Nrf2 expression in NRK-49F cells...
<p>A) Western blot and quantitative analysis for HO-1 expression, actin being used as loading contro...
(A, B) HEK293T cells were transfected with HA-tagged NRF2 and either wild type FLAG-tagged KEAP1 or ...
(A) Knockdown of Nrf2 with siNrf2 in control and HT-treated (200 μM) normoxic and hypoxic cells. The...
<p>The cells were transfected with a scramble control siRNA or Nrf2 siRNA, and were then treated wit...
<p>A FACS: the average of the median signal intensities in cells stained with anti-NRF2 antibodies ...
<p>Western blots illustrate Nrf2 protein concentration in whole cell lysate and nuclear fraction usi...
<p>ARPE-19 cells were treated with the indicated concentrations of LM for 48 h, or 40 μmol/L of LA o...
<p>(A) Anti-NRF2 Western Blot of tissue cell lysates after siRNA to the indicated screening hits. Tr...
A) Western blot analysis for phosphorylated p38 and total p38 in WT (238RM) and AT (AT129RM) cells t...
<p>NF-kB (A) was analyzed as described in materials and methods; Nrf2 mRNA (A) was analyzed by quant...
<p>(A) AGS cells were treated with DAS, DADS, and DATS (20 µM of each). After 1 h, the cells were ha...
<p>Confluent mAECs were pre-incubated with 250 µg/mL of AST or ASIV for 2 h, then washed and incubat...
<p><b>A</b>. Schematic diagram showing characteristics of cell lines with low (upper panel), moderat...
<p>Cells were incubated with or without ASTA (10 µM) for 1 h, and then stimulated with LPS (10 µg/ml...
<p>(A) Representative Western blot analysis of the effect of DMF on Nrf2 expression in NRK-49F cells...
<p>A) Western blot and quantitative analysis for HO-1 expression, actin being used as loading contro...
(A, B) HEK293T cells were transfected with HA-tagged NRF2 and either wild type FLAG-tagged KEAP1 or ...
(A) Knockdown of Nrf2 with siNrf2 in control and HT-treated (200 μM) normoxic and hypoxic cells. The...
<p>The cells were transfected with a scramble control siRNA or Nrf2 siRNA, and were then treated wit...
<p>A FACS: the average of the median signal intensities in cells stained with anti-NRF2 antibodies ...