Effects of aspirin and PNP on the liver weight to body weight ratio and oxidative stress related parameters.

<p><b>Panel A.</b> Measurement of liver weight to body weight ratio. <b>Panel B.</b> Measurement of the ferric reducing antioxidant Power (FRAP). CONT: normal mice group, PNP: mice treated with only PNP, ASA: mice administrated with aspirin, ASA+PNP: mice treated with PNP after aspirin intoxication. <b>Panel C.</b> Effect of Aspirin and PNP on Glutathione (GSH & GSSG) activities in liver tissue. GSH to GSSG ratio. <b>Panel D.</b> Effect of Aspirin and PNP on Glutathione (GSH & GSSG) activities in spleen tissue. GSH to GSSG ratio. Cont: normal mice, PNP: mice treated with only PNP, ASA: mice intoxicated with aspirin, ASA+PNP: mice treated with PNP after aspirin intoxication. ASA+VitC: mice treated with vitamin C after aspirin intoxication. “a” indicates the significant difference between the normal control and ASA intoxicated groups, and “b” indicates the significant difference between ASA intoxicated (toxin) and PNP post-treated groups. Each column represents mean ± SD, n = 6; (P^a<0.05, P^b<0.05).