<p>The plot for different Aβ peptides, (▴) 30 µM Cu<sup>2+</sup> alone, (♦) Aβ1-16, (▵) Aβ1-24, (•) Aβ1-29, (○) Aβ1-35, (◊) Aβ1-40, and (▿) Aβ25-35 in the presence of 30 µM Cu<sup>2+</sup>. Instead of generating H<sub>2</sub>O<sub>2</sub>, most Aβ peptides, except of Aβ25-35, inhibit the generation of H<sub>2</sub>O<sub>2</sub>. All measurements were measured after the fresh prepared samples were incubated at 37°C for 1 hr.</p
<p>(<b>A</b>) The fluorescence emission intensity of ANS at 25°C (λ<sub>exc</sub> = 350 nm) was plot...
<p>Tryptophan fluorescence quenching analysis showing the dose-response curve of the fluorescence va...
The characterization of biologically active peptides relies heavily on the study of their efficacy, ...
<p>The correlation between the fluorescence and the rate of H<sub>2</sub>O<sub>2</sub> scavenged for...
<p>The plot for different Aβ peptides, (▪) Aβ1-16, (♦) Aβ1-24, (▴) Aβ1-29, (○) Aβ1-35, (▾) Aβ1-40 an...
<p>(1)–Example of reaction rate constant determination for DCF formation when DCFH reacts with ROS. ...
<p>A) To characterize the baseline FP signal, the 6-carboxy-fluorescein labeled probe peptides p41 (...
<p>(A) Aβ42 (10 µM) was incubated with or without 20 µM of original or chimeric peptides for 12 or 2...
<p>Fluorescence response of H<sub>2</sub>DCFDA to various reactive oxygen and reactive nitrogen spec...
<p>A) Cartoon of experimental design. A metal-binding site is engineered into an FP and fluorescence...
<p>(A) Aβ1-16, (B)Aβ1-24, (C)Aβ1-29, (D)Aβ1-35, (E)Aβ1-40. The concentration of Aβ peptides was 10 µ...
<p><b>A. Progress curves of complemented fluorescence using purified protein.</b> The increasing flu...
<p>CD spectra for different Aβ peptides, (▿) Aβ1-16, (□) Aβ1-24, (•) Aβ1-29, (○) Aβ1-35, (▪) Aβ1-40,...
<p>(a) Intrinsic fluorescence spectrum of HspB2. The excitation wavelength was 295 nm. The excitatio...
<p>HFIP stocks of Aβ40, Aβ42, and Aβ43 were diluted in 10 mM phosphate buffer, pH 7.4(PB) followed b...
<p>(<b>A</b>) The fluorescence emission intensity of ANS at 25°C (λ<sub>exc</sub> = 350 nm) was plot...
<p>Tryptophan fluorescence quenching analysis showing the dose-response curve of the fluorescence va...
The characterization of biologically active peptides relies heavily on the study of their efficacy, ...
<p>The correlation between the fluorescence and the rate of H<sub>2</sub>O<sub>2</sub> scavenged for...
<p>The plot for different Aβ peptides, (▪) Aβ1-16, (♦) Aβ1-24, (▴) Aβ1-29, (○) Aβ1-35, (▾) Aβ1-40 an...
<p>(1)–Example of reaction rate constant determination for DCF formation when DCFH reacts with ROS. ...
<p>A) To characterize the baseline FP signal, the 6-carboxy-fluorescein labeled probe peptides p41 (...
<p>(A) Aβ42 (10 µM) was incubated with or without 20 µM of original or chimeric peptides for 12 or 2...
<p>Fluorescence response of H<sub>2</sub>DCFDA to various reactive oxygen and reactive nitrogen spec...
<p>A) Cartoon of experimental design. A metal-binding site is engineered into an FP and fluorescence...
<p>(A) Aβ1-16, (B)Aβ1-24, (C)Aβ1-29, (D)Aβ1-35, (E)Aβ1-40. The concentration of Aβ peptides was 10 µ...
<p><b>A. Progress curves of complemented fluorescence using purified protein.</b> The increasing flu...
<p>CD spectra for different Aβ peptides, (▿) Aβ1-16, (□) Aβ1-24, (•) Aβ1-29, (○) Aβ1-35, (▪) Aβ1-40,...
<p>(a) Intrinsic fluorescence spectrum of HspB2. The excitation wavelength was 295 nm. The excitatio...
<p>HFIP stocks of Aβ40, Aβ42, and Aβ43 were diluted in 10 mM phosphate buffer, pH 7.4(PB) followed b...
<p>(<b>A</b>) The fluorescence emission intensity of ANS at 25°C (λ<sub>exc</sub> = 350 nm) was plot...
<p>Tryptophan fluorescence quenching analysis showing the dose-response curve of the fluorescence va...
The characterization of biologically active peptides relies heavily on the study of their efficacy, ...