<p>(<b>A</b>) Levels of total cell-specific MP in plasma at time of CM onset: platelet-MP (PMP, white), endothelial-MP (EMP, light grey), erythrocytic-MP (EryMP, dark grey), monocytic-MP (MMP, black), leucocytic-MP (LMP, striped). (<b>B–F</b>) Cell-specific MP levels per µL of plasma at time of CM onset: non-infected (white bar), PbK (light grey bar), PbK<sup>1/2</sup> (dark grey bar), PbA (black bar). <b>B.</b> PMP. <b>C.</b> EMP. <b>D.</b> RMP. <b>E.</b> MMP. <b>F.</b> LMP. Data shown from <i>n = </i>25 healthy, <i>n = </i>20 PbK infected and <i>n = </i>10 PbK<sup>1/2</sup> infected mice showing signs of CM on day 6 and 7 p.i. and from <i>n = </i>23 PbA infected mice collected on day 6, 7 and 8 p.i., and represented as mean ± SEM. *p<0.05...
<p>(a) Representative histograms for the uptake of fluorescent beads by different kidney MPCs from 8...
<p>Spleens from B6, BXH2, [BXH2×B6]F1 and IRF1<sup>−/−</sup> mice were harvested prior to or six day...
Mice were infected A) Frequency and number of cDCs (CD11c+ PDCA-1−) and pDCs (CD11clow PDCA-1+) iden...
<p>PbK (closed triangle), PbK<sup>1/2</sup> (open triangle) or PbA (closed square) (<b>A</b>) PMP/µL...
<p>(<b>A</b>) Cytogram representation of total Annexin V<sup>+</sup> MP per µL of plasma in infected...
<p>Monthly blood collection from wild-type and <i>Npm1<sup>wt/c+</sup></i> mice without signs of mye...
a<p>Age of MPD: the age when MPD developed in <i>Npm1</i>-mutated mice.</p>b<p>The leukocytes (WBC),...
<p>(<b>A</b>) Monthly blood counts in peripheral blood were monitored in 24 <i>Npm1<sup>wt/wt</sup><...
<p>Mice were infected intranasally with 1,000 pfu of MHV68-H2bYFP and splenocytes were harvested at ...
C3H/HeN mice were susceptible to the development of CM (100% developed CM) and displayed similar mor...
<p>CBA/CaJ mice were infected with PbA-GFP or PyXL-RFP iRBC and subjected to craniotomy at the onset...
<p>PbA-infected mice exhibit small clusters of CD41+ platelets (blue) and patches of P-selectin (gre...
<p>Cells were isolated from spleen or BM from 7–11 week-old Myc (n = 5) or the Myc/latency (n = 5) m...
<p>(A) The levels of MPO in colon tissues. (B) The levels of MPO in mice plasma. ## <i>p<</i>0.01, #...
<p>(A–D) C57BL6 mice were infected with 1000PFU of the indicated virus either intranasally (A and C)...
<p>(a) Representative histograms for the uptake of fluorescent beads by different kidney MPCs from 8...
<p>Spleens from B6, BXH2, [BXH2×B6]F1 and IRF1<sup>−/−</sup> mice were harvested prior to or six day...
Mice were infected A) Frequency and number of cDCs (CD11c+ PDCA-1−) and pDCs (CD11clow PDCA-1+) iden...
<p>PbK (closed triangle), PbK<sup>1/2</sup> (open triangle) or PbA (closed square) (<b>A</b>) PMP/µL...
<p>(<b>A</b>) Cytogram representation of total Annexin V<sup>+</sup> MP per µL of plasma in infected...
<p>Monthly blood collection from wild-type and <i>Npm1<sup>wt/c+</sup></i> mice without signs of mye...
a<p>Age of MPD: the age when MPD developed in <i>Npm1</i>-mutated mice.</p>b<p>The leukocytes (WBC),...
<p>(<b>A</b>) Monthly blood counts in peripheral blood were monitored in 24 <i>Npm1<sup>wt/wt</sup><...
<p>Mice were infected intranasally with 1,000 pfu of MHV68-H2bYFP and splenocytes were harvested at ...
C3H/HeN mice were susceptible to the development of CM (100% developed CM) and displayed similar mor...
<p>CBA/CaJ mice were infected with PbA-GFP or PyXL-RFP iRBC and subjected to craniotomy at the onset...
<p>PbA-infected mice exhibit small clusters of CD41+ platelets (blue) and patches of P-selectin (gre...
<p>Cells were isolated from spleen or BM from 7–11 week-old Myc (n = 5) or the Myc/latency (n = 5) m...
<p>(A) The levels of MPO in colon tissues. (B) The levels of MPO in mice plasma. ## <i>p<</i>0.01, #...
<p>(A–D) C57BL6 mice were infected with 1000PFU of the indicated virus either intranasally (A and C)...
<p>(a) Representative histograms for the uptake of fluorescent beads by different kidney MPCs from 8...
<p>Spleens from B6, BXH2, [BXH2×B6]F1 and IRF1<sup>−/−</sup> mice were harvested prior to or six day...
Mice were infected A) Frequency and number of cDCs (CD11c+ PDCA-1−) and pDCs (CD11clow PDCA-1+) iden...