S1P induced Nf-κB activity is mediated by S1PR2 in BEAS-2B cells.

<p>Nf-κB luciferase reporter BEAS-2B cells were pretreated with S1PR2 inhibitor JTE 013 for 30 minutes before stimulation with S1P for 4 hours (n = 3). Cell lysates were analyzed for luciferase activity by Tecan iControl plate reader. Data are representative of means+SE. ANOVA with Tukey post hoc pairwise comparisons. ***P<0.001.