Comparison with recombinations detected by other methods.

<p>The length distribution of recombinations from other studies are compared with the length distributions of micro and macro recombinations inferred from PMEN1 (left column) or CC180 (right column). (A,B) The histogram shows a distribution of recombination sizes from an <i>in vivo</i> study, where 16 recombination events were collected from one patient suffering from pneumococcal infection over the period of 7 months <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004300#pgen.1004300-Hiller1" target="_blank">[14]</a>. Four lines correspond to four different functions based on the best-fit to the PMEN1 data (A) and CC180 data (B), as shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004300#pgen-1004300-g003" target="_blank">Figs. 3</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004300#pgen-1004300-g004" target="_blank">4</a>, respectively: micro-recombination size model (red), macro-recombination size model (green), full size distribution of the mixture-model 3 (brown), and the homogeneous, null model (pink). (C,D) The histogram shows a distribution of recombination sizes from an epidemiological study where 53 recombination events of another lineage, ST695, were inferred <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004300#pgen.1004300-Golubchik1" target="_blank">[15]</a>. The four lines are the same as above. (E,F) The histogram shows a distribution of recombination sizes from an <i>in vitro</i> transformation experiment <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004300#pgen.1004300-Croucher2" target="_blank">[13]</a>. The four lines are the same as above.