<p>Currents were induced by 1 mmol/l capsaicin.</p><p>* Significantly different from values in the WT control (first pulse) (P<0.05).</p><p>** Significantly different from values in the WT control (second pulse) (P<0.05).</p
<p>(Left) Bilayers made from TRPV1 membrane preparations were measured before compound addition (gra...
<p>A, Representative traces of currents induced by application of capsaicin (1 µM, 2 s) to WT or R19...
<p>(A) Representative whole-cell current traces of mV1 (shown in blue) and tsV1 (shown in red) elici...
<p>Currents were elicited by pH5.5. * Significantly different from values in the WT control (first p...
<p>(A) Amino acid sequence alignment of TRPV1. (B) Representative current trace of WT TRPV1 during r...
<p>(A) Representative current trace of WT TRPV1 during repeated exposure to 1 µM capsaicin. (B) Repr...
<p>(A) Representative whole-cell recordings elicited by 1 µM capsaicin (n = 5) in the presence of (B...
<p>Treatment with 5 μM capsaicin was performed at 20 s (indicated by dotted line). Because the respo...
<p>(A) Representative inside-out recordings of the application various LC-CoAs (0.1 µM) in the prese...
<p>(A) Representative whole-cell recordings (n = 7) and (B) inside-out recording (n = 5) of currents...
<p>A, The time coruse of the TRPV1 currents. The TRPV1 currents, expressed in HEK293 cells, were rec...
<p>(A) Representative whole-cell Ca<sup>2+</sup> currents recorded from HEK293T cells transfected wi...
<p>(A) Kinetic response in the Ca<sup>2+</sup> flux assay. Although 12 cells were evaluated in the s...
<p>(<b>A</b>): Representative current tracings recorded in the whole cell conditions (ramp protocol ...
<p>(<b>A</b>) TRPV1 current was activated by capsaicin (100 nM) and reversibly blocked by TRPV1 anta...
<p>(Left) Bilayers made from TRPV1 membrane preparations were measured before compound addition (gra...
<p>A, Representative traces of currents induced by application of capsaicin (1 µM, 2 s) to WT or R19...
<p>(A) Representative whole-cell current traces of mV1 (shown in blue) and tsV1 (shown in red) elici...
<p>Currents were elicited by pH5.5. * Significantly different from values in the WT control (first p...
<p>(A) Amino acid sequence alignment of TRPV1. (B) Representative current trace of WT TRPV1 during r...
<p>(A) Representative current trace of WT TRPV1 during repeated exposure to 1 µM capsaicin. (B) Repr...
<p>(A) Representative whole-cell recordings elicited by 1 µM capsaicin (n = 5) in the presence of (B...
<p>Treatment with 5 μM capsaicin was performed at 20 s (indicated by dotted line). Because the respo...
<p>(A) Representative inside-out recordings of the application various LC-CoAs (0.1 µM) in the prese...
<p>(A) Representative whole-cell recordings (n = 7) and (B) inside-out recording (n = 5) of currents...
<p>A, The time coruse of the TRPV1 currents. The TRPV1 currents, expressed in HEK293 cells, were rec...
<p>(A) Representative whole-cell Ca<sup>2+</sup> currents recorded from HEK293T cells transfected wi...
<p>(A) Kinetic response in the Ca<sup>2+</sup> flux assay. Although 12 cells were evaluated in the s...
<p>(<b>A</b>): Representative current tracings recorded in the whole cell conditions (ramp protocol ...
<p>(<b>A</b>) TRPV1 current was activated by capsaicin (100 nM) and reversibly blocked by TRPV1 anta...
<p>(Left) Bilayers made from TRPV1 membrane preparations were measured before compound addition (gra...
<p>A, Representative traces of currents induced by application of capsaicin (1 µM, 2 s) to WT or R19...
<p>(A) Representative whole-cell current traces of mV1 (shown in blue) and tsV1 (shown in red) elici...
DOI