<p>(A) Representative whole-cell recordings elicited by 1 µM capsaicin (n = 5) in the presence of (B) 25 µM PIP<sub>2</sub> (n = 12) or (C) 1 µM palmitoyl CoA (n = 9). (D) Representative whole-cell recordings elicited by acidic pH (pH = 5.5, n = 5) in the presence of (E) 1 µM palmitoyl CoA (n = 5). (F) Grouped data of the effects of PIP<sub>2</sub> and palmitoyl CoA on TRPV1 currents. *P<0.05. Dashed line denotes zero current level.</p
The effect of palmitic acid on the electrical potential differences delta psi across the inner mitoc...
<p>(<b>A</b>) TRPV1 current was activated by capsaicin (100 nM) and reversibly blocked by TRPV1 anta...
<p>(A) CF-PTEN is rapidly recruited to the plasma membrane anchor LDR by dimerization of FRB and FKB...
<p>(A) Representative whole-cell recordings (n = 7) and (B) inside-out recording (n = 5) of currents...
<p>(A) Representative inside-out recordings of the application various LC-CoAs (0.1 µM) in the prese...
<p>(A) Representative current trace of WT TRPV1 during repeated exposure to 1 µM capsaicin. (B) Repr...
<p>(A) Amino acid sequence alignment of TRPV1. (B) Representative current trace of WT TRPV1 during r...
<p>Currents were induced by 1 mmol/l capsaicin.</p><p>* Significantly different from values in the W...
<p>Current-voltage relationships after application of vehicle (Basal) or 2-arachidonoylglycerol (2-A...
<p>(Left) Bilayers made from TRPV1 membrane preparations were measured before compound addition (gra...
<p>(A) Representative intracellular paired pulse Ca<sup>2+</sup> recordings and grouped data of the ...
<p>Currents were elicited by pH5.5. * Significantly different from values in the WT control (first p...
<p>(A) Confocal images of cells expressing PJ-Dead (<i>top</i>), PJ-Sac (<i>middle</i>), INPP5E (<i>...
<p>A, The time coruse of the TRPV1 currents. The TRPV1 currents, expressed in HEK293 cells, were rec...
<p>(A) TRPV1 current traces repetitively activated by extracellular pH drop to 5.5 for 30 s with tim...
The effect of palmitic acid on the electrical potential differences delta psi across the inner mitoc...
<p>(<b>A</b>) TRPV1 current was activated by capsaicin (100 nM) and reversibly blocked by TRPV1 anta...
<p>(A) CF-PTEN is rapidly recruited to the plasma membrane anchor LDR by dimerization of FRB and FKB...
<p>(A) Representative whole-cell recordings (n = 7) and (B) inside-out recording (n = 5) of currents...
<p>(A) Representative inside-out recordings of the application various LC-CoAs (0.1 µM) in the prese...
<p>(A) Representative current trace of WT TRPV1 during repeated exposure to 1 µM capsaicin. (B) Repr...
<p>(A) Amino acid sequence alignment of TRPV1. (B) Representative current trace of WT TRPV1 during r...
<p>Currents were induced by 1 mmol/l capsaicin.</p><p>* Significantly different from values in the W...
<p>Current-voltage relationships after application of vehicle (Basal) or 2-arachidonoylglycerol (2-A...
<p>(Left) Bilayers made from TRPV1 membrane preparations were measured before compound addition (gra...
<p>(A) Representative intracellular paired pulse Ca<sup>2+</sup> recordings and grouped data of the ...
<p>Currents were elicited by pH5.5. * Significantly different from values in the WT control (first p...
<p>(A) Confocal images of cells expressing PJ-Dead (<i>top</i>), PJ-Sac (<i>middle</i>), INPP5E (<i>...
<p>A, The time coruse of the TRPV1 currents. The TRPV1 currents, expressed in HEK293 cells, were rec...
<p>(A) TRPV1 current traces repetitively activated by extracellular pH drop to 5.5 for 30 s with tim...
The effect of palmitic acid on the electrical potential differences delta psi across the inner mitoc...
<p>(<b>A</b>) TRPV1 current was activated by capsaicin (100 nM) and reversibly blocked by TRPV1 anta...
<p>(A) CF-PTEN is rapidly recruited to the plasma membrane anchor LDR by dimerization of FRB and FKB...