Effects of different concentrations of apamin on the rundown course of <i>I</i>_Ks in transfected HEK 293 cells.

<p>(A) An observation experiment without apamin treatment showing time-dependent rundown, obtained with the pulse protocol shown in the inset with chromanol 293B at the end. (B) The representative time course of <i>I</i>_Ks treated with different concentrations of apamin. (C) The time constant (τ) of the rundown curve with (n = 10) and without (n = 3) apamin.