Close-up view of residue pairs distinguished by strong interdomain coevolutionary signals.

<p>Panels <b>A</b>–<b>C</b> display the structural position of residue pairs listed in the first part of <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003624#pcbi-1003624-t001" target="_blank"><b>Table 1</b></a>, which make tertiary contacts. Panel <b>D</b> displays the location of all listed residues on the structure.