ipRGC intrinsic phototransduction persists in <i>Gna11</i>; <i>Gna14</i> DKO mice.

<p><b>A</b>. Representative voltage traces for ipRGC intrinsic light responses in WT and <i>Gna11</i>; <i>Gna14</i> DKO retinas at two 480 nm light intensities (7×10¹² and 7×10¹³ photons/cm²/sec). Horizontal bar represents light stimulation (60 sec). Vertical scale bar is 100 µV. <b>B</b>. Total number of spikes in ipRGCs light responses to two 480 nm light intensities (7×10¹² and 7×10¹³ photons/cm²/sec) and white light (267 mW/cm²). ipRGC light responses in <i>Gna11</i>; <i>Gna14</i> DKO were indistinguishable from WT. Student's t-test. Error bars represent s.e.m. <b>C–D</b>. Quantification of the number of spikes, in 1 second bins, during a 60 second pulse of either 7×10¹² photons/cm²/sec or 7×10¹³ photons/cm²/sec 480 nm light. Photoresponses in <i>Gna11</i>; <i>Gna14</i> DKO mice were indistinguishable from WT. Student's t-test. Error bars represent s.e.m.