Response characteristics of the three ipRGC types recorded from newborn <i>Arvicanthis</i> and mouse retinas.

<p><b>A</b>–<b>B</b>) response latency and C–D<b>)</b> light-evoked spike rate. (A) and (C) depicts the mean values (± SEM) and (C) and (D) the normalized response fitted with a sigmoidal Michaelis-Menten function. Light responses of single units measured from P0 – P3 retinas (4 retinas, n = 21, 51 and 21 for types I, II and III, respectively). Stimulus: 505 nm, 30 s. <b>E</b>–<b>J</b>) Response characteristics of the different ipRGCs types from newborn <i>Arvicanthis</i> (open circles, black curves) in comparison to ipRGCs from retinas of newborn C57BL/6 mice (filled circles, dashed curves). <i>Arvicanthis</i>: n = 93 cells (4 retinas; P0 – P3); mice: n = 39 cells (3 retinas; P0 – P2). <b>E</b>–<b>G</b>) Normalized response latency for cells of type I (E), II (F) and III (G). <b>H</b>–<b>J</b>) Normalized spike rate of type I (H), II (I) and III (J). All values are mean ± SEM. Stimulus: 505 nm, 30 s.