Receptor density.

<p>A) A schematic illustration of how temporal changes in receptor region area () and intensity are reflected. B) During the time period, both receptor intensity and area increase. The blue dashed line illustrates the isodensity line at T2. slopes greater than this isodensity line (i.e., illustrated by the green shaded area) represent intensity and area changes resulting in increasing density over this time period. Conversely, slopes less than the isodensity line (i.e., illustrated by the purple shaded area) would result from decreasing density over this time period. C–H) Distribution patterns of change in contact site area and intensity for DC-SIGN (C,E,G) and CD206 (D,F,H). Diamonds denote colocalized regions. Arrows annotate the temporal connection of the datapoints: blue for colocalized receptor regions. Time step arrows labeled “A” exhibit a significant change in area at . Time step arrows labeled “I” exhibit a significant change in intensity at . Dashed lines (nearly on top of the Area axes in (C–H) indicate the isodensity lines for zero hour colocalized datapoints. Statistical significance was determined by ANOVA and Tukey's post-hoc test with samples per donor for 1 and 4 hours and samples per donor for 0 h.