Survival of the parasite after RNAi of MAPKs <i>in vitro</i> and subsequent transfer into mice.

<p>Schistosomula were treated with GFP, SmJNK, SmCaMK2, and SmERK1 dsRNAs for two days and then injected into mice. After 37 days adult worms were recovered and counted. Each symbol in the chart represents worm counts from one mouse and the horizontal lines are median values per treatment group. Data were generated from 3 independent experiments and all treatments were statistical analyzed using Mann-Whitney U-test within each experiment (<i>P</i>≤0.05). The asterisk indicates a significance value of <i>P</i><0.022 for RNAi of SmJNK relative to the GFP control.