Effect of <i>Sm-</i>PLK1 silencing on schistosomula viability.
- Alessandra Guidi (146927)
- Nuha R. Mansour (146895)
- Ross A. Paveley (146889)
- Ian M. Carruthers (741479)
- Jérémy Besnard (741480)
- Andrew L. Hopkins (146939)
- Ian H. Gilbert (146934)
- Quentin D. Bickle (146947)
Publication date
May 2015
DOIAbstract
<p>(A-B) Survival of parasites treated with <i>Sm</i>-PLK1 long dsRNA compared with untreated controls (CTR) or controls treated with irrelevant dsRNA (IRR) in the absence (A) or presence (B) of hRBC. (C-D) Reduced viability and a lower percentage of blood feeding parasites in the presence of hRBC following <i>Sm</i>-PLK1 knockdown. The photomicrographs (C) are of schistosomula cultured for 3 weeks after RNAi treatment (scale bar = 100μm).</p
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