Effect of <i>Sm-</i>aPKC suppression in schistosomula.
- Alessandra Guidi (146927)
- Nuha R. Mansour (146895)
- Ross A. Paveley (146889)
- Ian M. Carruthers (741479)
- Jérémy Besnard (741480)
- Andrew L. Hopkins (146939)
- Ian H. Gilbert (146934)
- Quentin D. Bickle (146947)
Publication date
May 2015
DOIAbstract
<p>(A) <i>Sm-</i>aPKC expression in schistosomula 7 days after soaking with <i>Sm</i>-aPKC long dsRNA, irrelevant ds RNA (IRR) or untreated controls (CTR). (B) Light microscope images of schistosomula 4 weeks after the RNAi treatment. Top images:—wells without hRBC; bottom images:—wells with hRBC (scale bar = 100μm). Percent normal development (C) and percent survival (D) in cultures with hRBC (mean±SE triplicate cultures). Data are representative of 3 independent experiments.</p
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