<p>TCV from the RA CD4+ T cell and control LCLs analyzed in RA risk genes. <b>A</b>: JAK-STAT signaling pathway. <b>B</b>: T cell receptor signaling pathway. <b>C</b>: TNF signaling pathway. <b>D</b>: Cell adhesion pathway. <b>E</b>: Toll-like receptor signaling pathway. <b>F</b>: Antigen processing and presentation pathway. <b>G</b>: B cell development function pathway. The genes that are framed represent those genes showing significant genomic regulation profiles between RA CD4+ T cells and LCLs (P<0.05).</p
Objective: CD4+ T cells have been suggested as the most disease-relevant cell type in rheumatoid art...
Large-scale gene expression profiling of peripheral blood mononuclear cells from Rheumatoid Arthriti...
Rheumatoid arthritis (RA) is an immune-mediated disease affecting diarthrodial joints that remains a...
<p>TCV from the RA CD4+ T cell and control LCLs analyzed in RA risk genes. <b>A</b>: JAK-STAT signal...
<p>The type and quantity of significant eQTLs in RA CD4+ T cells and LCL cells are compared in the g...
<p>The pool of significantly up- and down-regulated genes in RA-differentiated cells was analyzed fo...
<p>(A) GO categories for comparison of differently expressed genes identified by microarray analysis...
<p><b>A</b>: completement system; <b>B</b>: agranulocyte adhesion and diapedesis; <b>C</b>: granuloc...
<p>(A) Venn diagrams of the gene expression patterns in NCCIT, EB<sub>RA</sub> and EB<sub>RA+GSK</su...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
International audienceThe etiopathogenesis of rheumatoid arthritis is partially understood; however,...
<p>A) Target enrichment scores representing the significances of overlaps between the targets of eac...
<p>A: The molecular network of 95 shared DEGs in RA <i>vs.</i> normal and CAD <i>vs.</i> normal indi...
<p>The relative transcript abundance of 51 transcripts in the KEGG TLR signaling pathway (map04620) ...
<p>A) A RA-perturbed network describing RA associated cellular processes in which 242 up-regulated R...
Objective: CD4+ T cells have been suggested as the most disease-relevant cell type in rheumatoid art...
Large-scale gene expression profiling of peripheral blood mononuclear cells from Rheumatoid Arthriti...
Rheumatoid arthritis (RA) is an immune-mediated disease affecting diarthrodial joints that remains a...
<p>TCV from the RA CD4+ T cell and control LCLs analyzed in RA risk genes. <b>A</b>: JAK-STAT signal...
<p>The type and quantity of significant eQTLs in RA CD4+ T cells and LCL cells are compared in the g...
<p>The pool of significantly up- and down-regulated genes in RA-differentiated cells was analyzed fo...
<p>(A) GO categories for comparison of differently expressed genes identified by microarray analysis...
<p><b>A</b>: completement system; <b>B</b>: agranulocyte adhesion and diapedesis; <b>C</b>: granuloc...
<p>(A) Venn diagrams of the gene expression patterns in NCCIT, EB<sub>RA</sub> and EB<sub>RA+GSK</su...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
International audienceThe etiopathogenesis of rheumatoid arthritis is partially understood; however,...
<p>A) Target enrichment scores representing the significances of overlaps between the targets of eac...
<p>A: The molecular network of 95 shared DEGs in RA <i>vs.</i> normal and CAD <i>vs.</i> normal indi...
<p>The relative transcript abundance of 51 transcripts in the KEGG TLR signaling pathway (map04620) ...
<p>A) A RA-perturbed network describing RA associated cellular processes in which 242 up-regulated R...
Objective: CD4+ T cells have been suggested as the most disease-relevant cell type in rheumatoid art...
Large-scale gene expression profiling of peripheral blood mononuclear cells from Rheumatoid Arthriti...
Rheumatoid arthritis (RA) is an immune-mediated disease affecting diarthrodial joints that remains a...