<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cells and using WGCNA, 16 genes expression modules (M) that characterize the CD4+ T cells were identified. For each gene expression module, the number of gene transcripts representing each module is shown, as well as the results of the immunological enrichment analysis.</p><p>Abbreviations: NS, No Significant.</p><p>* Significant (P<0.05).</p
<p>. Whole genome datasets of peripheral CD4<sup>+</sup> T cells were analyzed by hierarchical clust...
<p>(<b>A</b>) Gene set enrichment analysis was performed as described in <i>Materials and Methods</i...
Background: T-cells are involved in many immune functions. Each function is carried out by specific ...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>The new systems genetics approach is based on four steps that are performed before the <i>trans</...
<p>The type and quantity of significant eQTLs in RA CD4+ T cells and LCL cells are compared in the g...
<p>(A) Venn diagrams of the gene expression patterns in NCCIT, EB<sub>RA</sub> and EB<sub>RA+GSK</su...
<p>TCV from the RA CD4+ T cell and control LCLs analyzed in RA risk genes. <b>A</b>: JAK-STAT signal...
<p>To reveal genetic control of various subsets of CD4 T cells we compared gene expression profiles<...
Arker genes or control genes (grey symbols) between memory-phenotype and naive CD4 T cells. Values >...
Understanding the regulatory mechanisms of immune cells is a major topic in immunol-ogy research tod...
<p>A) A RA-perturbed network describing RA associated cellular processes in which 242 up-regulated R...
<p>A) Target enrichment scores representing the significances of overlaps between the targets of eac...
<p>. Whole genome datasets of peripheral CD4<sup>+</sup> T cells were analyzed by hierarchical clust...
<p>(<b>A</b>) Gene set enrichment analysis was performed as described in <i>Materials and Methods</i...
Background: T-cells are involved in many immune functions. Each function is carried out by specific ...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>Applying the new systems genetics approach for <i>trans</i>-eQTL identification in RA CD4+ T cell...
<p>The new systems genetics approach is based on four steps that are performed before the <i>trans</...
<p>The type and quantity of significant eQTLs in RA CD4+ T cells and LCL cells are compared in the g...
<p>(A) Venn diagrams of the gene expression patterns in NCCIT, EB<sub>RA</sub> and EB<sub>RA+GSK</su...
<p>TCV from the RA CD4+ T cell and control LCLs analyzed in RA risk genes. <b>A</b>: JAK-STAT signal...
<p>To reveal genetic control of various subsets of CD4 T cells we compared gene expression profiles<...
Arker genes or control genes (grey symbols) between memory-phenotype and naive CD4 T cells. Values >...
Understanding the regulatory mechanisms of immune cells is a major topic in immunol-ogy research tod...
<p>A) A RA-perturbed network describing RA associated cellular processes in which 242 up-regulated R...
<p>A) Target enrichment scores representing the significances of overlaps between the targets of eac...
<p>. Whole genome datasets of peripheral CD4<sup>+</sup> T cells were analyzed by hierarchical clust...
<p>(<b>A</b>) Gene set enrichment analysis was performed as described in <i>Materials and Methods</i...
Background: T-cells are involved in many immune functions. Each function is carried out by specific ...