Influence of dapagliflozin on physiologic and metabolic parameters in <i>db/db</i> and <i>db/m</i> mice at 20 weeks.

<p><i>db/m</i>, nondiabetic control mice; <i>db/db</i>, untreated diabetic mice; <i>db/db</i>+0.1 dapa, dapagliflozin (0.1 mg/kg)-treated diabetic mice; <i>db/db</i>+1.0 dapa, dapagliflozin (1.0 mg/kg)-treated diabetic mice; HbA1c, hemoglobin A1c. Data are presented as mean ± SEM;</p>a<p><i>P</i><0.05 vs. <i>db/m</i>,</p>b<p><i>P</i><0.05 vs. <i>db/db</i>,</p>c<p><i>P</i><0.05 vs. <i>db/db</i>+0.1 dapa.