The difference in A, the percentage of known cancer genes or damaging genes and B, the conservative score between five groups of mutated genes and control genes.

<p>Five groups of mutated genes were ranked in the top 50, 100, 150, 200 and 250 by betweenness coefficient of the network. Control genes are mutated genes with a betweenness coefficient of zero. The horizontal line parallel to the x axis represents the longitudinal coordinates of the control genes. * represents a significant difference (p<0.05).