Delayed tumor growth and tumor protection after IMI-Gel application.

<p>E.G7 thymoma cells (4×10⁵ s.c.), expressing SIINFEKL, were injected into the flank of C57BL/6 mice. After the tumor was palpable mice were immunized as indicated on two consecutive days in weekly intervals over a period of three weeks or left untreated. <b>A)</b> The tumor size and <b>B)</b> the survival were monitored. Depicted are the cumulative results of three independent experiments with n = 23 for emulsion gel and Aldara and n = 17 for untreated control. *Significant difference with p<0.05 by Mantel Cox test compared to the untreated control group.