<p>Levels of GSH/GSSG ratio, MnSOD activity, malondialdehyde (MDA) in liver (<b>A, C, E</b>) and gastrocnemius (<b>B, D, F</b>) of the mice described in Fig. 1 were measured and normalized to protein levels of the same samples as detailed in “<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0100875#s2" target="_blank">Methods and Materials</a>”. Results represent results of mean ± SD of 10 animals per group. *: P<0.05 vs. CD. **: P<0.01 vs. CD. #: P<0.05 vs. HFD +0.1% carbs. ##: P<0.01 vs. HFD +0.1% carbs. $$: P<0.01 vs. HFD +5% carbs.</p
<p>A, Body weights of both normal diet (ND) and HFD-induced mice at the age of 44 weeks. B, Blood gl...
<p>The mice received HFCD for four weeks and then the HFCD diet was changed to a CD diet (HFCD/CD). ...
Both dietary fat and carbohydrates (Carbs) may play important roles in the development of insulin re...
<p>At the end of the 5-week experiment, animals were fasted for 8 h and liver and skeletal muscle sa...
<p>C57BL/6 (B6) mice were fed the regular chow diet (CD) <i>ad libitum</i> or HFD plus 0.1%, 5%, 10%...
<p>(A) Tissue NAD<sup>+</sup> was determined from snap frozen liver, gastrocnemius, brown fat and wh...
<p>Tissue oxidative stress was evaluated after 5 or 8 weeks feeding with HFD by protein nitrotyrosyl...
<p>The average results ± SE are shown. (*p<0.05 vs corresponding NC, n = 6–9 mice per group).</p
<p>(A) Basal oxygen consumption measured by a polarographic method in gastrocnemius (GSCN) and tibia...
<p>Eight weeks old C57BL/6J mice were weight-matched and fed control fed (CF) on HFD (n = 7–8) and m...
<p>Cytokine protein levels were measured in eWAT lysates from WT (black bars) and OPN KO (grey bars)...
<p>After one week of HFru or HFat feeding, the activity of NADPH oxidase (<b>A</b>) and intracellula...
<p>At the end of the 5-week experiment, animals were fasted for 8 h. Liver (<b>A</b>) and skeletal m...
<p>(A) the GSH/GSSG ratio was significantly decreased in both gastrocnemius muscle and liver samples...
<p>(<b>A</b>) Fasting blood glucose was measured once a week after an 8-hour fast. (<b>B</b>) Plasma...
<p>A, Body weights of both normal diet (ND) and HFD-induced mice at the age of 44 weeks. B, Blood gl...
<p>The mice received HFCD for four weeks and then the HFCD diet was changed to a CD diet (HFCD/CD). ...
Both dietary fat and carbohydrates (Carbs) may play important roles in the development of insulin re...
<p>At the end of the 5-week experiment, animals were fasted for 8 h and liver and skeletal muscle sa...
<p>C57BL/6 (B6) mice were fed the regular chow diet (CD) <i>ad libitum</i> or HFD plus 0.1%, 5%, 10%...
<p>(A) Tissue NAD<sup>+</sup> was determined from snap frozen liver, gastrocnemius, brown fat and wh...
<p>Tissue oxidative stress was evaluated after 5 or 8 weeks feeding with HFD by protein nitrotyrosyl...
<p>The average results ± SE are shown. (*p<0.05 vs corresponding NC, n = 6–9 mice per group).</p
<p>(A) Basal oxygen consumption measured by a polarographic method in gastrocnemius (GSCN) and tibia...
<p>Eight weeks old C57BL/6J mice were weight-matched and fed control fed (CF) on HFD (n = 7–8) and m...
<p>Cytokine protein levels were measured in eWAT lysates from WT (black bars) and OPN KO (grey bars)...
<p>After one week of HFru or HFat feeding, the activity of NADPH oxidase (<b>A</b>) and intracellula...
<p>At the end of the 5-week experiment, animals were fasted for 8 h. Liver (<b>A</b>) and skeletal m...
<p>(A) the GSH/GSSG ratio was significantly decreased in both gastrocnemius muscle and liver samples...
<p>(<b>A</b>) Fasting blood glucose was measured once a week after an 8-hour fast. (<b>B</b>) Plasma...
<p>A, Body weights of both normal diet (ND) and HFD-induced mice at the age of 44 weeks. B, Blood gl...
<p>The mice received HFCD for four weeks and then the HFCD diet was changed to a CD diet (HFCD/CD). ...
Both dietary fat and carbohydrates (Carbs) may play important roles in the development of insulin re...