<p>Cytokine protein levels were measured in eWAT lysates from WT (black bars) and OPN KO (grey bars) mice fed normal chow or HFD. Values are averages ± standard error. 8–10 mice per group. * p<0.05 vs diet-matched WT, # p<0.05 vs strain-matched, normal chow.</p
<p>(A) FACS detection of M1-type, F4/80+CD11b+CD11c+ pro-inflammatory macrophages in adipose tissue ...
<p>HFD significantly altered the body weight (A), and induced glucose intolerance (B) in C57BL/6J mi...
<p>The bars represent the means and SEM of n = 3–15 mice per diet group. The pleiotropic cytokines w...
<p>Cytokine protein levels measured in eWAT lysates from WT (black bars) and 12/15LO KO (gray bars) ...
<p>(A) Growth curve of C57Bl/6 WT male mice over 8-week ad libitum feeding with standard chow (red) ...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a–f) qPCR analysis for cytokines (a...
<p>(A) Representative histological images of eWAT from mouse groups. (B) Quantitation of subcutaneou...
<p>Euglycemic hyperinsulinemic clamp study results are shown. (A) Ginf, (B) GDR, and (C) HGO rates i...
<p>(A) Representative western blot of OPN isoforms with apparent molecular weights of approximately ...
<p>(A) Lean mass (n = 10). (B) Fat mass (n = 10). (C) Representative images of WAT histological exam...
<p>In bold the trend for difference as compared to NCD (p<0.1, Mann Whitney U-Test with Bonferroni's...
<p>APOE*3Leiden transgenic mice were fed a HFD for 12 weeks and sacrificed at the time points indica...
(A) Body weights of WT and DKO mice in CD-fed states (WT, n = 7; DKO, n = 6), and (B) HDF-fed states...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a) Bodyweight development upon LFD ...
(A) Food consumption was measured every week to calculate average amounts of food intake per day. *P...
<p>(A) FACS detection of M1-type, F4/80+CD11b+CD11c+ pro-inflammatory macrophages in adipose tissue ...
<p>HFD significantly altered the body weight (A), and induced glucose intolerance (B) in C57BL/6J mi...
<p>The bars represent the means and SEM of n = 3–15 mice per diet group. The pleiotropic cytokines w...
<p>Cytokine protein levels measured in eWAT lysates from WT (black bars) and 12/15LO KO (gray bars) ...
<p>(A) Growth curve of C57Bl/6 WT male mice over 8-week ad libitum feeding with standard chow (red) ...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a–f) qPCR analysis for cytokines (a...
<p>(A) Representative histological images of eWAT from mouse groups. (B) Quantitation of subcutaneou...
<p>Euglycemic hyperinsulinemic clamp study results are shown. (A) Ginf, (B) GDR, and (C) HGO rates i...
<p>(A) Representative western blot of OPN isoforms with apparent molecular weights of approximately ...
<p>(A) Lean mass (n = 10). (B) Fat mass (n = 10). (C) Representative images of WAT histological exam...
<p>In bold the trend for difference as compared to NCD (p<0.1, Mann Whitney U-Test with Bonferroni's...
<p>APOE*3Leiden transgenic mice were fed a HFD for 12 weeks and sacrificed at the time points indica...
(A) Body weights of WT and DKO mice in CD-fed states (WT, n = 7; DKO, n = 6), and (B) HDF-fed states...
<p>MAP3K8-ko and WT mice were fed a LFD or HFD during 16 weeks. (a) Bodyweight development upon LFD ...
(A) Food consumption was measured every week to calculate average amounts of food intake per day. *P...
<p>(A) FACS detection of M1-type, F4/80+CD11b+CD11c+ pro-inflammatory macrophages in adipose tissue ...
<p>HFD significantly altered the body weight (A), and induced glucose intolerance (B) in C57BL/6J mi...
<p>The bars represent the means and SEM of n = 3–15 mice per diet group. The pleiotropic cytokines w...