<p>Airway hyperreactivity was directly measured by changes in airway resistance and lung compliance through a methacholine dose curve. (A) Dynamic airway resistance (p<0.0001) and (B) Dynamic compliance (p = 0.0005) measurements were made 7 days after CARDS toxin exposure and analyzed using 2-way ANOVA.</p
<p>Mice (n = 8) were sensitized with OVA/Alum and received 3 OVA or PBS inhalation challenges. TLR-2...
<p>A-B) H&E stained lung sections demonstrating inflammation in OVA (panel A) or OVA + rCARDS toxin ...
<p>The airway resistance (R), after increasing concentrations of methacholine (0–10 mg/ml), was meas...
<p>All animals were sensitised i.p. with OVA/Al (OH)<sub>3</sub> and subsequently challenged i.n. wi...
<p>(a) Lung resistance in LPS-rich and LPS-free OVA challenged mice 48 hours following three OVA cha...
<p>To determine bronchial hyperresponsiveness, lung function analysis was performed using the IPL an...
<p>AHR was measured using plethysmography 24 h after the final OVA challenge, in mice given various ...
<p>Bronchoconstrictive response to increasing doses of nebulized methacholine (MCH) following pretre...
<p>WT or JH<sup>-/-</sup> mice were intranasally exposed to OAAH or PBS for 2 weeks, as described in...
<p>The animals were sacrificed on day 25 to determine tissue inflammation and on day 26 for airway h...
<p>Bronchoconstrictive responses to increasing doses of nebulized methacholine (MCH) in: (<b>A</b>) ...
a<p>Cytokines showing an increase over basal levels when animals are exposed to active CARDS toxin. ...
<p>Mice (n = 8) were sensitized with OVA/Alum and received a first series of 3 OVA inhalation challe...
Responsiveness is expressed as the peak Ers or Rrs after administration of 160 μg/kg methacholine mi...
<p>Mice were sensitized on days 0 and 7 either by oral administration of ovalbumin (1000 μg) and cho...
<p>Mice (n = 8) were sensitized with OVA/Alum and received 3 OVA or PBS inhalation challenges. TLR-2...
<p>A-B) H&E stained lung sections demonstrating inflammation in OVA (panel A) or OVA + rCARDS toxin ...
<p>The airway resistance (R), after increasing concentrations of methacholine (0–10 mg/ml), was meas...
<p>All animals were sensitised i.p. with OVA/Al (OH)<sub>3</sub> and subsequently challenged i.n. wi...
<p>(a) Lung resistance in LPS-rich and LPS-free OVA challenged mice 48 hours following three OVA cha...
<p>To determine bronchial hyperresponsiveness, lung function analysis was performed using the IPL an...
<p>AHR was measured using plethysmography 24 h after the final OVA challenge, in mice given various ...
<p>Bronchoconstrictive response to increasing doses of nebulized methacholine (MCH) following pretre...
<p>WT or JH<sup>-/-</sup> mice were intranasally exposed to OAAH or PBS for 2 weeks, as described in...
<p>The animals were sacrificed on day 25 to determine tissue inflammation and on day 26 for airway h...
<p>Bronchoconstrictive responses to increasing doses of nebulized methacholine (MCH) in: (<b>A</b>) ...
a<p>Cytokines showing an increase over basal levels when animals are exposed to active CARDS toxin. ...
<p>Mice (n = 8) were sensitized with OVA/Alum and received a first series of 3 OVA inhalation challe...
Responsiveness is expressed as the peak Ers or Rrs after administration of 160 μg/kg methacholine mi...
<p>Mice were sensitized on days 0 and 7 either by oral administration of ovalbumin (1000 μg) and cho...
<p>Mice (n = 8) were sensitized with OVA/Alum and received 3 OVA or PBS inhalation challenges. TLR-2...
<p>A-B) H&E stained lung sections demonstrating inflammation in OVA (panel A) or OVA + rCARDS toxin ...
<p>The airway resistance (R), after increasing concentrations of methacholine (0–10 mg/ml), was meas...