Binding affinities of ASOs for the SOD-1 minigene mRNA spiked into the denatured nuclear extract and mRNA transcribed and spliced in the nuclear extract.
- Walt F. Lima (449545)
- Timothy A. Vickers (605766)
- Josh Nichols (605767)
- Cheryl Li (605768)
- Stanley T. Crooke (449546)
Publication date
July 2014
DOIAbstract
<p>Differences in the binding affinities (ΔK<sub>d</sub>) between the two targets were calculated by dividing the K<sub>d</sub> of the ASOs for the SOD-1 minigene mRNA transcribed and spliced in the nuclear extract by the K<sub>d</sub> for the SOD-1 minigene mRNA spiked into the denatured nuclear extract.</p
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