Pulmonary gene expression profiles as function of time after <i>B. pertussi</i>s infection.

<p>Fold changes in expression were calculated compared to naive mice and significant gene expression results (FR≥1.5, <i>p</i>-value≤0.001) are visualized as heatmap (mean of n = 3). In total, 558 genes were found to be differentially regulated, divided in 446 up-regulated genes (red) and 112 down-regulated genes (green). Genes not exceeding a fold change of 1.5 are depicted as basal level (black) at this time point. Results are divided in 5 clusters representing up/down-regulation and time of involvement including corresponding GO-BP terms and KEGG pathways.