<p>The conserved DFG motif is highlighted in blue box; the gatekeeper residue is highlighted in red box; residue corresponding to Met341 in c-Src is highlighted in purple box; several extra stretches of amino acids are highlighted in green box.</p
<p><i>Left:</i> alignment of the kinase domain, covering the region 83–422 of FAM69A. The sequences ...
<p>(a) SMARCAD1, (b) GSG2, (c) NUP35, (d) NEK5, (e) KIF23 and (f) CEP170. MSA illustrates the conser...
<p>The identities are underlined by asterisks. The predicted signal sequences are in lower case. The...
<p>Sequences have been truncated after the C-terminal lobe. The conserved HRD and DFG motifs have be...
<p>Representative alignment of MAPKs is shown. Residues identified via CHAIN as distinctive of MAPKs...
<p>The consensus sequences of Protein kinase domain (Pkinase, pfam00069) and Catalytic domain of Pro...
<p>(A) Structure and domain arrangement in full-length Csk (PDB ID 1K9A). (B) Sequence and structura...
<p>Amino acid sequences were obtained from the Phytozome database. The numbers indicate the distance...
<p>Structure-based sequence alignment of the <i>S. aureus</i> PknB kinase domain with the kinase dom...
<p>A) Key conserved interactions in MAPKs, using a p38α as a representative model (PDBID: 4LOO), wit...
<p>The crystal structure of the SH2 domain of the Src-family kinase Lck bound to a high-affinity pho...
<p>The alignment is generated with the programs Multalin [<a href="http://www.plosone.org/article/in...
<p><b>A</b>. Sub-domains of the protein kinase domain. Consensus sequences DL(R/A)A(A/R)N in subdoma...
<p>The protein names are indicated at the left of the alignment. The key residues in the kinase doma...
<p>Cysteine residues coloured yellow are found in 100% of the aligned sequences. Residues coloured b...
<p><i>Left:</i> alignment of the kinase domain, covering the region 83–422 of FAM69A. The sequences ...
<p>(a) SMARCAD1, (b) GSG2, (c) NUP35, (d) NEK5, (e) KIF23 and (f) CEP170. MSA illustrates the conser...
<p>The identities are underlined by asterisks. The predicted signal sequences are in lower case. The...
<p>Sequences have been truncated after the C-terminal lobe. The conserved HRD and DFG motifs have be...
<p>Representative alignment of MAPKs is shown. Residues identified via CHAIN as distinctive of MAPKs...
<p>The consensus sequences of Protein kinase domain (Pkinase, pfam00069) and Catalytic domain of Pro...
<p>(A) Structure and domain arrangement in full-length Csk (PDB ID 1K9A). (B) Sequence and structura...
<p>Amino acid sequences were obtained from the Phytozome database. The numbers indicate the distance...
<p>Structure-based sequence alignment of the <i>S. aureus</i> PknB kinase domain with the kinase dom...
<p>A) Key conserved interactions in MAPKs, using a p38α as a representative model (PDBID: 4LOO), wit...
<p>The crystal structure of the SH2 domain of the Src-family kinase Lck bound to a high-affinity pho...
<p>The alignment is generated with the programs Multalin [<a href="http://www.plosone.org/article/in...
<p><b>A</b>. Sub-domains of the protein kinase domain. Consensus sequences DL(R/A)A(A/R)N in subdoma...
<p>The protein names are indicated at the left of the alignment. The key residues in the kinase doma...
<p>Cysteine residues coloured yellow are found in 100% of the aligned sequences. Residues coloured b...
<p><i>Left:</i> alignment of the kinase domain, covering the region 83–422 of FAM69A. The sequences ...
<p>(a) SMARCAD1, (b) GSG2, (c) NUP35, (d) NEK5, (e) KIF23 and (f) CEP170. MSA illustrates the conser...
<p>The identities are underlined by asterisks. The predicted signal sequences are in lower case. The...