MBP depolarizes the resting membrane potential.

<p>(A) Representative neuronal resting membrane potentials (RMPs) recorded before and after HBSS or 50 µg/mL MBP treatment in current-clamp mode. (B) Statistical analysis of RMP changes. Compared to those in HBSS treatment (ns, not significant; paired, two-tailed t-test; n = 10), neuronal RMPs were depolarized after MBP treatment (***P<0.001; paired, two-tailed t-test; n = 11).