BJe prevents the LPS-stimulated release of IL-1β and TNF-α in THP-1 monocytes.

<p>The cells were treated with increasing concentrations of BJe (0.05–0.5 mg/ml for 30 min) prior to add LPS (500 ng/ml; 3 hs). Then, secretion of IL-6 (A), IL-1β (B) and TNF-α (C) in the media was evaluated by ELISA assay. Data are the mean ± SEM of three independent experiments performed in triplicate. *** p<0.001, significant differences <i>vs</i> untreated cultures; ^§ p<0.05 and ^§§§ p<0.001, significant differences <i>vs</i> LPS treated cells (ANOVA followed by Student-Newman Keuls multiple comparisons test).