The relative expression level of candidate genes is correlated with observed antiviral phenotype.

<p>Upper panels: mRNA expression of <i>Sult1a1</i><b>(A)</b> and <i>Il27</i><b>(B)</b> in irrelevant shRNA-transduced cells compared to shRNAs against the indicated gene measured by qRT-PCR. <i>Gapdh</i> was used as internal control for normalization. The results shown are the average from two independent experiments. Lower panels: percentages of GFP-positive cells after HSV-GFP infection in cells previously transduced with irrelevant shRNA (lacZ and luciferase) or targeting shRNA for <i>Sult1a1</i><b>(A)</b> or <i>Il27</i><b>(B)</b>. Data shown are representative of 3 independent experiments. ns, not significant; ***<i>P</i><0.001 compared to negative control by one-way ANOVA with Dunnett's post-test.