Heat map of IFX treatment effect for CD14⁺ cells in different diseases.

<p>In each heat map, columns correspond to patients and rows to probe sets. Separate heat maps are shown for three diseases and two cell types as indicated. Color is the log₂ difference in expression at 2 or 10 weeks relative to baseline as specified by the blue and gold bars, respectively (patients are in same order for each set of columns for each disease). Probe set clustering was accomplished using Euclidean distance and complete linkage. Only genes for which p<.005 for one of the time points are shown. BL = baseline. Font color for gene names indicate whether the probe set was significant at p<.05 at 2 weeks (purple), 10 weeks (green) or both (gray). For all heat maps, the columns (patients) are sorted first by responders/non-responders, and then by change in disease activity at 10 weeks relative to baseline (DAS28 for RA and PsA, PASI for Ps), which is shown beneath each heat map (responders are black bars, non-responders are gray bars).