Heatmap of samples clustered by global gene expression, showing samples generally cluster by treatment group.

<p>The heatmap was generated by performing unsupervised hierarchical clustering of the gene expression data, and represents the natural grouping of patients according to the similarity of their gene expression profiles, as represented in the dendrogram. This clustering is based only on the gene expression data, and is done without respect to the treatment group. The dendrogram arm lengths are a measure of sample similarity, and they provide a simplified view of which samples are most similar to one another.