KEGG pathways with enrichment of genes annotated to CpG sites of significant cis-mQTLs in human pancreatic islets.

Décio L. Eizirik (2227888)
Michael Sammeth (179044)
Thomas Bouckenooghe (179047)
Guy Bottu (179049)
Giorgia Sisino (179051)
Mariana Igoillo-Esteve (179053)
Fernanda Ortis (179055)
Izortze Santin (179057)
Maikel L. Colli (179059)
Jenny Barthson (179062)
Luc Bouwens (179065)
Linda Hughes (179068)
Lorna Gregory (113497)
Gerton Lunter (27174)
Lorella Marselli (179072)
Piero Marchetti (179074)
Mark I. McCarthy (145748)
Miriam Cnop (179076)

March 2012

(A, B) 1,416 genes were significantly up-regulated by the cytokines IL-1β+IFN-γ in at least 4 out...

Genetic regulation of RNA splicing in human pancreatic islets

Goutham Atla
Sílvia Bonàs-Guarch
Mirabai Cuenca-Ardura
Anthony Beucher
Daniel J.M. Crouch
Javier Garcia-Hurtado
Ignasi Moran
T2DSystems consortium
Manuel Irimia
Rashmi B Prasad
Anna L. Gloyn
Lorella Marselli
Mara Suleiman
Thierry Berney
Eelco J P de Koning
Julie Kerr-Conte
Francois Pattou
John A. Todd
Lorenzo Piemonti
Jorge Ferrer

May 2022

Here we provide summary statistics data of splicing and gene expression QTLs (sQTLs and eQTLs, respe...

Downregulation of Type II Diabetes Mellitus and Maturity Onset Diabetes of Young Pathways in Human Pancreatic Islets from Hyperglycemic Donors.

Taneera, Jalal
Storm, Petter
Groop, Leif

January 2014

Although several molecular pathways have been linked to type 2 diabetes (T2D) pathogenesis, it is un...

KEGG pathways with enrichment of genes that exhibit differential DNA methylation in pancreatic islets of 34 non-diabetic compared with 15 T2D donors.

Tasnim Dayeh (428020)
Petr Volkov (428018)
Sofia Salö (531658)
Elin Hall (428021)
Emma Nilsson (428023)
Anders H. Olsson (428022)
Clare L. Kirkpatrick (364109)
Claes B. Wollheim (364112)
Lena Eliasson (73900)
Tina Rönn (253292)
Karl Bacos (531659)
Charlotte Ling (253302)

March 2014

Hypermethylated genes in T2D islets are in bold, P-values have been adjusted for multiple ...

Genomic distribution of CpG sites of significantly identified mQTLs in human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

(A) Chromosomal distribution of CpG sites of significant cis- and trans-mQTL...

Identified cis-mQTLs/eQTLs where methylation of CpG sites is a potential mediator of genetic association with mRNA expression in human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

Causal Inference Test (CIT) was used to test if associations between SNPs identified in the ci...

Number of significant eQTL results in the human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

Only SNPs of significant mQTLs are included in the eQTL analysis.SNPs of significant ci...

Distribution of individual sites that exhibit differential DNA methylation in human islets from 15 T2D versus 34 non-diabetic donors.

Tasnim Dayeh (428020)
Petr Volkov (428018)
Sofia Salö (531658)
Elin Hall (428021)
Emma Nilsson (428023)
Anders H. Olsson (428022)
Clare L. Kirkpatrick (364109)
Claes B. Wollheim (364112)
Lena Eliasson (73900)
Tina Rönn (253292)
Karl Bacos (531659)
Charlotte Ling (253302)

March 2014

(A) The chromosomal location of the 1,649 sites that exhibit differential DNA methylation ...

KEGG pathways significantly enriched by genes differentially expressed between MEi cells and BM-MSCs.

Mei Ling Lim (630703)
Brandon Nick Sern Ooi (630704)
Philipp Jungebluth (630705)
Sebastian Sjöqvist (630706)
Isabell Hultman (630707)
Greg Lemon (630708)
Ylva Gustafsson (630709)
Jurate Asmundsson (630710)
Silvia Baiguera (630711)
Iyadh Douagi (630712)
Irina Gilevich (630713)
Alina Popova (630714)
Johannes Cornelius Haag (630715)
Antonio Beltrán Rodríguez (630716)
Jianri Lim (630717)
Agne Liedén (118589)
Magnus Nordenskjöld (118610)
Evren Alici (594712)
Duncan Baker (630718)
Christian Unger (630719)
Tom Luedde (180139)
Ivan Vassiliev (630720)
Jose Inzunza (250616)
Lars Ährlund-Richter (194428)
Paolo Macchiarini (630721)

September 2014

Pathways were identified by DAVID Functional Annotation and ranked by P-value with a cutoff of 0....

Number of significant mQTL results in human pancreatic islets when including imputed genotyped data.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

Significance threshold <0.05 after correction for multiple testing.Correction value cis...

Top 3 KEGG pathways for differentially expressed genes in pancreatic adenocarcinoma.

Ting Xi (5040059)
Guizhi Zhang (756306)

March 2018

Top 3 KEGG pathways for differentially expressed genes in pancreatic adenocarcinoma.</p

Depiction and distance analysis of associations between genotype and DNA methylation of significant mQTLs in human pancreatic islets.

PLOS Genetics (2206858)

December 2014

Depiction of (A) the most significant cis-mQTL; rs1771445 vs. cg02372404, and (B...

CIT analysis identifies mQTLs where DNA methylation potentially mediates genetic associations with mRNA expression in human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

(A) Depiction of possible relationship models between genotype as a causal factor (G), DNA...

Fred P. Davis (17322)
Sean R. Eddy (5840)

May 2013

(A) Genome browser view of RNA-seq and ChIP-seq data over several genes that are more highly expr...

KEGG pathway analysis of up regulated genes in the HC high/HT low group.

Dong Kyung Sung (287830)
Yun Sil Chang (287827)
So Yoon Ahn (287829)
Se In Sung (287831)
Hye Soo Yoo (287832)
Soo Jin Choi (287828)
Soo Yoon Kim (787233)
Won Soon Park (287834)

August 2015

The HC high/HT low group was analyzed for functional annotation by KEGG pathway mapping.KE...

IPA of cytokine-modified genes.

Décio L. Eizirik (2227888)
Michael Sammeth (179044)
Thomas Bouckenooghe (179047)
Guy Bottu (179049)
Giorgia Sisino (179051)
Mariana Igoillo-Esteve (179053)
Fernanda Ortis (179055)
Izortze Santin (179057)
Maikel L. Colli (179059)
Jenny Barthson (179062)
Luc Bouwens (179065)
Linda Hughes (179068)
Lorna Gregory (113497)
Gerton Lunter (27174)
Lorella Marselli (179072)
Piero Marchetti (179074)
Mark I. McCarthy (145748)
Miriam Cnop (179076)

March 2012

(A, B) 1,416 genes were significantly up-regulated by the cytokines IL-1β+IFN-γ in at least 4 out...

Genetic regulation of RNA splicing in human pancreatic islets

Goutham Atla
Sílvia Bonàs-Guarch
Mirabai Cuenca-Ardura
Anthony Beucher
Daniel J.M. Crouch
Javier Garcia-Hurtado
Ignasi Moran
T2DSystems consortium
Manuel Irimia
Rashmi B Prasad
Anna L. Gloyn
Lorella Marselli
Mara Suleiman
Thierry Berney
Eelco J P de Koning
Julie Kerr-Conte
Francois Pattou
John A. Todd
Lorenzo Piemonti
Jorge Ferrer

May 2022

Here we provide summary statistics data of splicing and gene expression QTLs (sQTLs and eQTLs, respe...

Downregulation of Type II Diabetes Mellitus and Maturity Onset Diabetes of Young Pathways in Human Pancreatic Islets from Hyperglycemic Donors.

Taneera, Jalal
Storm, Petter
Groop, Leif

January 2014

Although several molecular pathways have been linked to type 2 diabetes (T2D) pathogenesis, it is un...

KEGG pathways with enrichment of genes that exhibit differential DNA methylation in pancreatic islets of 34 non-diabetic compared with 15 T2D donors.

Tasnim Dayeh (428020)
Petr Volkov (428018)
Sofia Salö (531658)
Elin Hall (428021)
Emma Nilsson (428023)
Anders H. Olsson (428022)
Clare L. Kirkpatrick (364109)
Claes B. Wollheim (364112)
Lena Eliasson (73900)
Tina Rönn (253292)
Karl Bacos (531659)
Charlotte Ling (253302)

March 2014

Hypermethylated genes in T2D islets are in bold, P-values have been adjusted for multiple ...

Genomic distribution of CpG sites of significantly identified mQTLs in human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

(A) Chromosomal distribution of CpG sites of significant cis- and trans-mQTL...

Identified cis-mQTLs/eQTLs where methylation of CpG sites is a potential mediator of genetic association with mRNA expression in human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

Causal Inference Test (CIT) was used to test if associations between SNPs identified in the ci...

Number of significant eQTL results in the human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

Only SNPs of significant mQTLs are included in the eQTL analysis.SNPs of significant ci...

Distribution of individual sites that exhibit differential DNA methylation in human islets from 15 T2D versus 34 non-diabetic donors.

Tasnim Dayeh (428020)
Petr Volkov (428018)
Sofia Salö (531658)
Elin Hall (428021)
Emma Nilsson (428023)
Anders H. Olsson (428022)
Clare L. Kirkpatrick (364109)
Claes B. Wollheim (364112)
Lena Eliasson (73900)
Tina Rönn (253292)
Karl Bacos (531659)
Charlotte Ling (253302)

March 2014

(A) The chromosomal location of the 1,649 sites that exhibit differential DNA methylation ...

KEGG pathways significantly enriched by genes differentially expressed between MEi cells and BM-MSCs.

Mei Ling Lim (630703)
Brandon Nick Sern Ooi (630704)
Philipp Jungebluth (630705)
Sebastian Sjöqvist (630706)
Isabell Hultman (630707)
Greg Lemon (630708)
Ylva Gustafsson (630709)
Jurate Asmundsson (630710)
Silvia Baiguera (630711)
Iyadh Douagi (630712)
Irina Gilevich (630713)
Alina Popova (630714)
Johannes Cornelius Haag (630715)
Antonio Beltrán Rodríguez (630716)
Jianri Lim (630717)
Agne Liedén (118589)
Magnus Nordenskjöld (118610)
Evren Alici (594712)
Duncan Baker (630718)
Christian Unger (630719)
Tom Luedde (180139)
Ivan Vassiliev (630720)
Jose Inzunza (250616)
Lars Ährlund-Richter (194428)
Paolo Macchiarini (630721)

September 2014

Pathways were identified by DAVID Functional Annotation and ranked by P-value with a cutoff of 0....

Number of significant mQTL results in human pancreatic islets when including imputed genotyped data.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

Significance threshold <0.05 after correction for multiple testing.Correction value cis...

Top 3 KEGG pathways for differentially expressed genes in pancreatic adenocarcinoma.

Ting Xi (5040059)
Guizhi Zhang (756306)

March 2018

Top 3 KEGG pathways for differentially expressed genes in pancreatic adenocarcinoma.</p

Depiction and distance analysis of associations between genotype and DNA methylation of significant mQTLs in human pancreatic islets.

PLOS Genetics (2206858)

December 2014

Depiction of (A) the most significant cis-mQTL; rs1771445 vs. cg02372404, and (B...

CIT analysis identifies mQTLs where DNA methylation potentially mediates genetic associations with mRNA expression in human pancreatic islets.

Anders H. Olsson (428022)
Petr Volkov (428018)
Karl Bacos (531659)
Tasnim Dayeh (428020)
Elin Hall (428021)
Emma A. Nilsson (655665)
Claes Ladenvall (135128)
Tina Rönn (253292)
Charlotte Ling (253302)

November 2014

(A) Depiction of possible relationship models between genotype as a causal factor (G), DNA...

Fred P. Davis (17322)
Sean R. Eddy (5840)

May 2013

(A) Genome browser view of RNA-seq and ChIP-seq data over several genes that are more highly expr...

KEGG pathway analysis of up regulated genes in the HC high/HT low group.

Dong Kyung Sung (287830)
Yun Sil Chang (287827)
So Yoon Ahn (287829)
Se In Sung (287831)
Hye Soo Yoo (287832)
Soo Jin Choi (287828)
Soo Yoon Kim (787233)
Won Soon Park (287834)

August 2015

The HC high/HT low group was analyzed for functional annotation by KEGG pathway mapping.KE...

IPA of cytokine-modified genes.

Décio L. Eizirik (2227888)
Michael Sammeth (179044)
Thomas Bouckenooghe (179047)
Guy Bottu (179049)
Giorgia Sisino (179051)
Mariana Igoillo-Esteve (179053)
Fernanda Ortis (179055)
Izortze Santin (179057)
Maikel L. Colli (179059)
Jenny Barthson (179062)
Luc Bouwens (179065)
Linda Hughes (179068)
Lorna Gregory (113497)
Gerton Lunter (27174)
Lorella Marselli (179072)
Piero Marchetti (179074)
Mark I. McCarthy (145748)
Miriam Cnop (179076)

March 2012

(A, B) 1,416 genes were significantly up-regulated by the cytokines IL-1β+IFN-γ in at least 4 out...

Genetic regulation of RNA splicing in human pancreatic islets

Goutham Atla
Sílvia Bonàs-Guarch
Mirabai Cuenca-Ardura
Anthony Beucher
Daniel J.M. Crouch
Javier Garcia-Hurtado
Ignasi Moran
T2DSystems consortium
Manuel Irimia
Rashmi B Prasad
Anna L. Gloyn
Lorella Marselli
Mara Suleiman
Thierry Berney
Eelco J P de Koning
Julie Kerr-Conte
Francois Pattou
John A. Todd
Lorenzo Piemonti
Jorge Ferrer

May 2022

Here we provide summary statistics data of splicing and gene expression QTLs (sQTLs and eQTLs, respe...

Downregulation of Type II Diabetes Mellitus and Maturity Onset Diabetes of Young Pathways in Human Pancreatic Islets from Hyperglycemic Donors.

Taneera, Jalal
Storm, Petter
Groop, Leif

January 2014

Although several molecular pathways have been linked to type 2 diabetes (T2D) pathogenesis, it is un...

KEGG pathways with enrichment of genes annotated to CpG sites of significant <i>cis</i>-mQTLs in human pancreatic islets.

Abstract

Extracted data

KEGG pathways with enrichment of genes annotated to CpG sites of significant <i>cis</i>-mQTLs in human pancreatic islets.

Abstract

Extracted data

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