Similar genes are differentially expressed and PcG modified when comparing fibroblasts and pancreatic islets in both human and mouse.

<p>(A) Genome browser view of RNA-seq and ChIP-seq data over several genes that are more highly expressed in human pancreatic islet cells and more strongly H3K27me3 modified in fibroblasts. Axes similar to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063407#pone-0063407-g001" target="_blank">Figure 1A</a>. (B,C) Similar sets of genes are differentially expressed and modified when comparing fibroblasts and pancreatic islets in both human and mouse. Plots similar to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063407#pone-0063407-g001" target="_blank">Figure 1B</a>. Bold labels denote genes shown on both human and mouse plots. Data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063407#pone.0063407-Cabili1" target="_blank">[57]</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063407#pone.0063407-Koche1" target="_blank">[64]</a>, the Illumina Human Bodymap (<a href="http://www.illumina.com" target="_blank">http://www.illumina.com</a>), the Roadmap Epigenomics Project (<a href="http://roadmapepigenomics.org" target="_blank">http://roadmapepigenomics.org</a>), and two other public datasets (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063407#pone.0063407.s001" target="_blank">Table S1</a>).