The mRNA expression levels of core clock genes.

<p>A to C, Comparison of core clock genes in the liver (A), muscle (B), and kidney (C) between C57BL/6N (B6) and <i>ob/ob</i> (<i>ob</i>) mice at 35 weeks of age. n = 3–8 per group. D, Per1 mRNA levels in mature adipocyte fraction (MAF) and stromal vascular fraction (SVF) of B6 and <i>ob</i> mice. WAT of 8-week-old mice was fractionated as described in Materials and Methods section. n = 6 per group. Values are mean ± SEM. **P<0.01; ***P<0.001. ^$$$P<0.001, compared to MAF of B6 mice.^#P<0.05, compared to SVF of B6 mice.